Hi Shane, another curious case is the crystal structure of a signal receiver domain of Desulfovibrio desulfuricans (PDB code: 3cg0, Patskovsky et al., to be published), as discussed in Sippl (2009) Curr. Opin. Struct. Biol.
Best, -Markus > Hi ccp4bb, > > I'm putting together a talk for some peers that highlights strengths and > weaknesses of structural models for the outsider. For one point, I'd like to > find some examples of proteins that show very different conformations between > different copies in the ASU. One example I know of is c-Abl (1OPL), which > crystallizes with both autoinhibited and active forms in the ASU, with > dramatically different domain organization. I'd like to find some additional > examples - can anyone suggest some other structures that have multiple copies > with large structural variations? > > Thanks in advance! > > Shane Caldwell > McGill University > >
