Dear Giulliana,
I imagine this may well be of assistance:-

*J. Appl. Cryst.* (2009). *42*, 540-544    [ doi:10.1107/S0021889809012370
<http://dx.doi.org/10.1107/S0021889809012370> ]
HATODAS II - heavy-atom database system with potentiality scoringM. Sugahara
<http://scripts.iucr.org/cgi-bin/citedin?search_on=name&author_name=Sugahara,%20M.>,
Y. Asada
<http://scripts.iucr.org/cgi-bin/citedin?search_on=name&author_name=Asada,%20Y.>,
H. Shimada
<http://scripts.iucr.org/cgi-bin/citedin?search_on=name&author_name=Shimada,%20H.>,
H. Taka
<http://scripts.iucr.org/cgi-bin/citedin?search_on=name&author_name=Taka,%20H.>
and N. Kunishima
<http://scripts.iucr.org/cgi-bin/citedin?search_on=name&author_name=Kunishima,%20N.>


Best wishes,
John

On Mon, Jun 29, 2015 at 1:47 PM, Giulliana Rangel <
[email protected]> wrote:

> Dear all,
>
> I'm looking for a method to solve the phase problem. Thus, I would like
> some help about heavy-atom derivatives.
>
> What is the best heavy-atom to make soaking? I tried Iodine (because my
> protein have a lot of tyrosines), but no results...
>
> I read some papers about quick-soak, its a good method? Using platine, Hg,
> Br...
>
> Any suggestions? Thank you so much.
>
> Best wishes,
>
> --
> Giulliana Rangel
> M.S. Biotechnology Program - UNIFESP
> Structural Biology Laboratory
> Phone: +55 (12) 3309-9698
> 330 Talim St
> ZIP CODE 12231-280
> São José dos Campos - SP/ BR
>
>


-- 
Professor John R Helliwell DSc

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