Dear Crystallographers,

I don't think there is any feasible way crystallographically to distinguish 
between nitrate and carbonate or bicarbonate-correct? But that is not my main 
question.

My main question is: given that nitrate and carbonate are both very important 
and also very different physiologically, and therefore they must be 
distinguished/recognized by cells, how is this done, since the ions are so 
similar in structure? Is there some aspect of these ions that differs 
dramatically of which I am not aware? What kind of "handles" could a protein 
grab onto to distinguish between nitrate and carbonate/bicarbonate?

JPK


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Jacob Pearson Keller, PhD
Research Scientist
HHMI Janelia Research Campus / Looger lab
Phone: (571)209-4000 x3159
Email: [email protected]<mailto:[email protected]>
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