Dear Crystallographers, I am working to solve an human protein structure which has a domain sequence identity of 24% with domain of another protein. As Phaser as well as Molrep failed to give any definite solution (TFZ=3.7 from MR), I want to ask, if solution structure of another protein having domain sequence similarity of 25% or a homology model can be used as a template for MR? Many thanks and Regards Nishant
-- Dr. Nishant Kumar Varshney, Research Associate, C/O Dr. Sameena Khan, Drug Discovery Research Center, Translational Health Science and Technology Institute (THSTI) NCR Biotech Science Cluster, 3rd Milestone, Faridabad – Gurgaon Expressway, Faridabad – 121001 (HARYANA), India Ph: +91- 0129-2876477 <+91%20129%20287%206477> Mob: 8390564690
