Dear Colleagues
Hope to find you all well and healthy.

I have a question regarding Rmerge. In recent years, we have published our
crystallographic structures in highly respected journals using CC1/2,
I/sigma(I), completeness and multiplicity as quality parameters for our
diffraction data.

Recently this year, We submitted a paper using the same strategy, but one
of the reviewers asked us to provide the Rmerge, arguing that providing
this data was compulsory and it was important to estimate radiation damage.

We replied to the editor arguing that Rmerge should not be used as a
quality parameter, as suggested by more recent literature, such as the
article published by Karplus and Diederichs (10.1016/j.sbi.2015.07.003). We
also argued that there are modern and efficient methods to estimate
radiation damage ( doi.org/10.1107/S1600576718005241;
doi.org/10.1107/S0907444909040177). It is my opinion that an experienced
crystallographer can even  monitor radiation damage over the course of data
processing.

And our paper was rejected !!!!!!!!!!!!!!!! due to the fact I did not
provide Rmerge which I certainly could have done If I found necessary.

Journals like Nature ((https://www.nature.com › documents › nr-tables-xray
<https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&ved=2ahUKEwiigtb19uHwAhWS3YUKHSB1AdkQFjABegQIAxAD&url=https%3A%2F%2Fwww.nature.com%2Fdocuments%2Fnr-tables-xray.doc&usg=AOvVaw1RbfYvNeiEM07FBEOohMig>
) and even IUCr Journals (
https://journals.iucr.org/f/services/structuralcommunications/) still list
Rmerge as a data to be reported. I always took this as a suggestion since
there are people still using Rmerge for data cutoff, but I never took this
as if Rmerge was a compulsory data to be reported.

I would like to hear the opinion of this community. Should we compulsorily
report Rmerge?  If so, Why?

Cheers,

Cristy
-- 

*Cristina Nonato*
Associate Professor
Laboratório de Cristalografia de Proteínas
Faculdade de Ciências Farmacêuticas de Ribeirão Preto
University of São Paulo

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