Hi Eike,

Instead of AKTA Pure I purchased a combo of AKTA Go (€24k with air sensor) and 
AKta start (€9k with frac collector). It provides two parallel workstations 
with AKTA start handling the dirty job of loading lysates onto affinity 
cartridges and the GO doing clean SEC stages. For multiple proteins isolation, 
this combo beats AKTA Pure flat out for half price. Note that AKTA Start can’t 
be equipped with an air sensor, and sample loading need to be done by time 
control. However, we didn’t find it to be an issue.
Also, AKTA Start needs a separate version of Uncocrn suite for an extra €1k. So 
we skipped that and control the system via the built-in touchscreen.

As for the longevity, we need to see. Six months into active operation went 
smooth—the only malfunction was the Windows update breaking network card 
drivers.

Best,

Oleksiy


Dr Oleksiy Kovtun
Max-Planck Research Group Leader
Molecular Mechanisms of Membrane Trafficking
Max-Planck-Institute for Multidisciplinary Sciences
City-Campus, Hermann-Rein-Str. 3, 37075 Göttingen
Germany
Email: [email protected]<mailto:[email protected]>
https://www.mpinat.mpg.de/kovtun
Phone:+49-551-3899-410


On 16. Sep 2022, at 09:39, Schulz, Eike-Christian 
<[email protected]<mailto:[email protected]>> wrote:

Dear all,

I am considering to purchase a chromatography system for routine protein 
purification. The device is supposed to be used in a multi-user environment, 
hence ease of use, ease of training and ease of maintenance is important. I am 
rather looking for a robust system people like to use than a system that comes 
with many bells and whistles that no one dares to touch.


  *   Is there any particularly _bad_ experience with either system?



  *   Is there any specific advantage of one system over the other?



  *   Does anyone have experience about (long-term) stability / performance of 
the systems?



  *   Do you think the higher price-point of the Aekta systems is justified?



With best regards,

Eike




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