On 12/01/2026 18:44, Ezennubia, Purity wrote:

Hello everyone,
Hello Purity Ezennubia,
I just upgraded my macOS from Sequoia to Tahoe
very courageous of you
 and I have been having issues opening coot from sbgrid.
OK, are you going to tell us more about that?
 I have the standalone coot 1.1.19 I downloaded from homebrew
Latest Coot from homebrew is 1.1.20 - thanks Yoshitaka Moriwaki
 but its not functioning well. When I click two atoms to real space refine nothing happens.

i) Coot has changed to "Select First"

ii) One rarely needs to refine with a double atom pick, i.e. use tandem or sphere refine instead

iii) if you really want click click refine then you need to click on "Range/Pair" before you click on your atoms and then Refine -> RSR Refine Range.

Please anyone with assistance on this i will really appreciate it. I have been unable to do any refinement since Friday.

Nightmare!

Paul.


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