Dear Purity,
A personalised answer will be forthcoming but in the meantime,
since you are asking about the causes of anisotropy in diffraction
data, you would certainly benefit from reading the document at
https://staraniso.globalphasing.org/anisotropy_about.html
in which all technical terms used are explained in the accompanying
Glossary at
https://staraniso.globalphasing.org/staraniso_glossary.html
With best wishes,
Gerard.
--
On Wed, Jan 21, 2026 at 05:58:42PM +0000, Ezennubia, Purity wrote:
> Hello everyone,
>
> It's becoming almost a regular norm for my crystals to be anisotropic when I
> look at the diffraction data. Its really unideal for me because when the data
> is anisotropic my R-work and R-free values are usually high when compared to
> some lucky data I got that was not anisotropic.
>
> I would like to hear from other people in this forum what causes a crystal to
> diffract anisotropically going to different resolution in the hkl axis.
>
> Thank you,
> Purity
>
> Kelechi Purity Ezennubia
> Graduate research assistant
> Department of Chemistry & Biochemistry
> Baylor University
> Clinger lab C161R
> [email protected]
>
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