Thank you, Gerard, for the document recommendation. Kelechi Purity Ezennubia Graduate research assistant Department of Chemistry & Biochemistry Baylor University Clinger lab C161R [email protected] ________________________________ From: Gerard Bricogne <[email protected]> Sent: Wednesday, January 21, 2026 1:29:55 PM To: Ezennubia, Purity <[email protected]> Cc: [email protected] <[email protected]>; Star Aniso <[email protected]> Subject: Re: [ccp4bb] Anisotropy diffraction data user discussion
[You don't often get email from [email protected]. Learn why this is important at https://aka.ms/LearnAboutSenderIdentification ] Dear Purity, A personalised answer will be forthcoming but in the meantime, since you are asking about the causes of anisotropy in diffraction data, you would certainly benefit from reading the document at https://nam02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fstaraniso.globalphasing.org%2Fanisotropy_about.html&data=05%7C02%7CPurity_Ezennubia1%40BAYLOR.EDU%7C27c5ce1c69ac44cb2d7108de592377a3%7C22d2fb35256a459bbcf4dc23d42dc0a4%7C0%7C0%7C639046206077920452%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=xuRCFinfgQSFb0Ysfa6tuJsli%2BMFm6PjnANxnYi6Eug%3D&reserved=0<https://staraniso.globalphasing.org/anisotropy_about.html> in which all technical terms used are explained in the accompanying Glossary at https://nam02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fstaraniso.globalphasing.org%2Fstaraniso_glossary.html&data=05%7C02%7CPurity_Ezennubia1%40BAYLOR.EDU%7C27c5ce1c69ac44cb2d7108de592377a3%7C22d2fb35256a459bbcf4dc23d42dc0a4%7C0%7C0%7C639046206077955875%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=JjXzau8KZJ1iSiWGEFN6lC6ZB0pyKu17GE3wiVBDG1s%3D&reserved=0<https://staraniso.globalphasing.org/staraniso_glossary.html> With best wishes, Gerard. -- On Wed, Jan 21, 2026 at 05:58:42PM +0000, Ezennubia, Purity wrote: > Hello everyone, > > It's becoming almost a regular norm for my crystals to be anisotropic when I > look at the diffraction data. Its really unideal for me because when the data > is anisotropic my R-work and R-free values are usually high when compared to > some lucky data I got that was not anisotropic. > > I would like to hear from other people in this forum what causes a crystal to > diffract anisotropically going to different resolution in the hkl axis. > > Thank you, > Purity > > Kelechi Purity Ezennubia > Graduate research assistant > Department of Chemistry & Biochemistry > Baylor University > Clinger lab C161R > [email protected] > > ######################################################################## > > To unsubscribe from the CCP4BB list, click the following link: > https://nam02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.jiscmail.ac.uk%2Fcgi-bin%2FWA-JISC.exe%3FSUBED1%3DCCP4BB%26A%3D1&data=05%7C02%7CPurity_Ezennubia1%40BAYLOR.EDU%7C27c5ce1c69ac44cb2d7108de592377a3%7C22d2fb35256a459bbcf4dc23d42dc0a4%7C0%7C0%7C639046206077981621%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=%2FNFBLlEo1kXrBdTtMCdJYsdqQ5dt3ZK46WU2%2FdkMo0U%3D&reserved=0<https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1> > > This message was issued to members of > https://nam02.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.jiscmail.ac.uk%2FCCP4BB&data=05%7C02%7CPurity_Ezennubia1%40BAYLOR.EDU%7C27c5ce1c69ac44cb2d7108de592377a3%7C22d2fb35256a459bbcf4dc23d42dc0a4%7C0%7C0%7C639046206078006083%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=3UasUfxrLsv9GPPACgVFEyAmy1%2FuSnn2iqYRZ3kw%2FrU%3D&reserved=0<http://www.jiscmail.ac.uk/CCP4BB>, > a mailing list hosted by > https://nam02.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.jiscmail.ac.uk%2F&data=05%7C02%7CPurity_Ezennubia1%40BAYLOR.EDU%7C27c5ce1c69ac44cb2d7108de592377a3%7C22d2fb35256a459bbcf4dc23d42dc0a4%7C0%7C0%7C639046206078029660%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=Pmgx46YPcGV%2FnfBepayFNnRVheh7SNCCmMUEC0W0lFQ%3D&reserved=0<http://www.jiscmail.ac.uk/>, > terms & conditions are available at > https://nam02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.jiscmail.ac.uk%2Fpolicyandsecurity%2F&data=05%7C02%7CPurity_Ezennubia1%40BAYLOR.EDU%7C27c5ce1c69ac44cb2d7108de592377a3%7C22d2fb35256a459bbcf4dc23d42dc0a4%7C0%7C0%7C639046206078050886%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=NytWiUJBsEjl3OepK9ULkzKPUpwxCOR2uy7Wh0CiXMM%3D&reserved=0<https://www.jiscmail.ac.uk/policyandsecurity/> ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
