Hi,
phenix.refine can try to add ions automatically as part of refinement. Try
it out to get a 2nd opinion. The method it uses is described here:
https://pmc.ncbi.nlm.nih.gov/articles/PMC3975891/
Good luck!
Pavel


On Mon, Jul 13, 2026 at 8:03 AM amit gaur <
[email protected]> wrote:

> Hi All,
>
> I am currently trying to model calcium and sodium ions in Coot, but I am
> encountering atomic clashes after placing them. Based on the electron
> density, I am confident that these sites are occupied.
>
> Has anyone experienced this before or have any suggestions on how to
> handle these clashes? I would appreciate any advice.
>
> Thank you!
>
> *Amit Gaur, *
> *Department of Biomedical Science,*
> *College of Medicine,*
> *Florida State University,*
> *1115 W Call St, Tallahassee, FL,32304*
>
>
>
>
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