Hello,

you can also use anomalous scattering to identify the element type, either by 
collecting data above and below absorption edges, or in cases edges can't be 
accessed, e.g. sodium, by refining f".

Check out this paper and our webpage in case you are interested in an 
experimental approach.
https://journals.iucr.org/d/issues/2024/10/00/gin5001/index.html
https://www.diamond.ac.uk/Instruments/Mx/I23.html


Best regards,
Armin



________________________________
From: CCP4 bulletin board <[email protected]> on behalf of Martin Mal? 
<[email protected]>
Sent: Monday, July 13, 2026 17:37
To: [email protected] <[email protected]>
Subject: Re: [ccp4bb] Question About Modeling Calcium and Sodium in Coot

Dear Amit Gaur,

You can have a look on our work on the MetalCoord program:
https://github.com/Lekaveh/MetalCoordAnalysis
https://journals.iucr.org/d/issues/2024/12/00/von5002/index.html

It can also give you external distance and angle restraints which can be used 
in refmac, servalcat, phenix.refine or Coot. In Coot 0.9, select Calculate -> 
Modules -> Restraints, and then Restraints -> Read Extra Refmac Restraints... 
In Coot 1, click on the + with arrow in the right top corner and select 
Restraints, and then Restraints -> Import Restraints...

Good luck! Please keep us updated how it goes.
Cheers,
Martin

On 13/07/2026 14:02, amit gaur wrote:
Hi All,

I am currently trying to model calcium and sodium ions in Coot, but I am 
encountering atomic clashes after placing them. Based on the electron density, 
I am confident that these sites are occupied.

Has anyone experienced this before or have any suggestions on how to handle 
these clashes? I would appreciate any advice.

Thank you!

Amit Gaur,
Department of Biomedical Science,
College of Medicine,
Florida State University,
1115 W Call St, Tallahassee, FL,32304




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