>From today's Washington Post:
http://antiwrap.com/x486038d8a5576

Brain Study Shows Differences Between Gays, Straights

By Rob Stein
Washington Post Staff Writer
Monday, June 23, 2008; A12

Is there such a thing as a "gay brain"? And, if so, are some people born with 
brains that make them more likely to be homosexual? Or do the brains of gay 
people develop differently in response to experiences?

Those are some of the thorny questions that have been raised by a provocative 
new study that found striking differences between the brains of homosexuals and 
heterosexuals in both men and women.

Some scientists say the new findings are part of an increasingly convincing 
body of evidence that suggests sexual orientation results from fundamental 
developmental differences that are probably caused by hormonal exposures in the 
womb.

"This research is pointing to basic differences in the brain between homosexual 
and heterosexual people that are likely there right from the beginning," said 
Sandra F. Witelson, a professor of psychiatry and behavioral neurosciences at 
McMaster University in Ontario. "These could be reflecting some genetic or 
hormonal factors that predetermine your sexual orientation."

Others, however, argue that such research is far from conclusive.

"I remain skeptical," said William Byne, a professor of psychiatry at Mount 
Sinai School of Medicine in New York. "There's been a history of jumping to 
conclusions and overinterpreting findings in this field."

Several earlier studies have found what appear to be differences between the 
brains of gay and straight people. In 1991, brain scientist Simon LeVay 
reported that the hypothalamus, which is involved in sexual behavior, tended to 
be smaller in gay men. Other researchers subsequently showed that the brains of 
gay and straight people appeared likely to respond differently to sexual 
images. The researchers who conducted the new study previously reported that 
the brains of gay and straight men seemed to react differently to suspected 
pheromones -- odors thought to be involved in sexual arousal.

But such research is fraught with uncertainty, and it could not rule out that 
the findings were the result of changes that occurred in response to 
experiences and behaviors, rather than being inborn.

"The next question was 'If there is a difference, could there be differences in 
parts of the brain that have nothing to do with sexual behaviors?' " said 
Ivanka Savic of the Karolinska Institute in Stockholm, who led the new research 
published online last week by the Proceedings of the National Academy of 
Sciences.

So Savic and her colleague Per Lindstrom first used magnetic resonance imaging, 
or MRI, to compare the symmetry of the brains of 25 straight men and 25 
straight women with those of 20 gay men and 20 gay women.

Gay men tended to have brains that were more like those of straight women than 
of straight men -- the right and left sides were about the same size, the 
researchers found. Gay women's brains tended to be more like those of straight 
men than of straight women -- the right side tended to be slightly larger than 
the left.

Next, the researchers used positron emission tomography (PET) scans to examine 
how a part of the brain involved in processing emotions -- the amygdala -- was 
connected to other brain regions. Again they found that gay men tended to be 
more like straight women, with a stronger link between the amygdala and regions 
involved in emotions. Gay women tended to be more like straight men, with 
stronger connections to motor functions.

Savic and Lindstrom stressed that their findings need to be confirmed by 
additional research and that it remains unclear how the differences might 
affect behavior.

While other researchers agreed, some said the findings about the amygdala could 
help explain why gay men tend to respond to emotional situations more like 
women and gay women more like men, and could even play a role in their sexual 
orientation.

"This ancient structure is involved in 'orienting' our attention to 
biologically important stimuli in our environment (such as attractive partners 
. . .)," Qazi Rahman, who studies sexual orientation at Queen Mary, University 
of London, wrote in an e-mail.

Others said that that interpretation was highly speculative, but at the very 
least the findings support the idea that there tend to be fundamental 
differences in brain structure, supporting the idea that sexual orientation is 
inborn.

"This suggests that there's something going on during development that 
influences sexuality and the brain," LeVay said. "It points more persuasively 
to some early biological difference."

LeVay and other researchers said the findings fit with studies that found gay 
people tended to have different ratios in the lengths of their fingers and in 
the frequency of imperceptible clicking sounds in the ear.

"There's this cluster of interrelated findings," said Richard A. Lippa, a 
professor of psychology at California State University at Fullerton, who has 
found evidence that in gay men, the hair on the back of the head is more likely 
to curl counterclockwise than in straight men. "These are all biological 
markers that something must have gone on early in development."

These findings also fit with studies showing gay men tend to choose professions 
that typically attract women, such as teaching and social work, and have verbal 
and other cognitive skills that tend to be more like women's, he said.

"You get a sort of global shift in gender traits in gay people and straight 
people that affects not only their sexual orientation but other things as 
well," LeVay said.

Many researchers suspect that changes may be the result of the levels of 
hormones, such as testosterone, that fetuses are exposed to in the womb.

"We see the same asymmetries in the brains of rats and mice, and in rats and 
mice testosterone seems to be controlling it prenatally," said Marc Breedlove, 
a neuroscientist at Michigan State University.

But researchers say many questions remain about all this research. And there 
are as many differences within groups individuals of the same sexual 
orientation as between those of different orientation. Moreover, the new work 
involved adults, meaning there is no way to know with certainty when the 
structures and connections formed and why.

"It takes a snapshot of a group of people at a particular age," said Anne 
Fausto-Sterling, a professor of biology and gender studies at Brown University. 
"Even if there are reliable brain differences, it doesn't tell you anything 
about how those brain differences came into being." 

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