Making vaccine's is a tricky business. The fundamental problem is that
you have to disable the pathogen (virus or bacteria) enough to make it
not dangerous while leaving enough parts intact enough that the immune
system will recognize it and produce an antibody. We don't have a
complete understanding of the microbiology of most viruses and
bacteria yet, which makes the production of an initial vaccine
difficult and then it is complicated by the fact that both viruses and
bacteria tend to mutate, necessitating new versions of existing
vaccines once we do work out the basic biological mechanics of the
pathogen.

My daughter has had the Prevnar immunization, which protects against
the pneumococcal bacteria that causes bacterial meningitis. But if I
recall, it only protects against 5 or 7 or so serotypes (different
strains). I don't know how many serotypes there are but it is the sort
of thing where they put their effort into getting the most common ones
right and if you get an obscure one, well, hopefully the existing
antibodies will be of some help when your body is trying to fight off
the novel pathogen.

Our understanding of the microbiology of pathogens is still quite
immature but there is some great work being done. But the more we
know, the more questions there are. Like the fact that there is a
chickenpox vaccine now. Should we routinely vaccinate children against
a virus that isn't lethal? Are we setting ourselves up for something
bad down the road if we lose chicken pox as a low-level common
infection? Will it be replaced by something much nastier? I'm not sure
yet and I'm leery of over vaccinating just like we now know that we
have done way too much over medication with antibiotics.

Judah

On Wed, Nov 4, 2009 at 12:33 PM, G Money <[email protected]> wrote:
>
> Makes sense....dunno why I thought that method would only fly for viruses.
> Makes sense for bacteria as well.
>
> Why can we vaccinate against some viral and bacterial diseases, and not
> others? For instance, could we produce a meningitis vaccine against both the
> viral and bacterial strains? Anyone know?

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