According to Super Tuning and Modifying Holley Carburetors by Dave Emmanuel page 23 reads  "..., part number Holley 0-3310-1 has the same venturi and throttle bore dimensions as the 0-3310-2, -3, -4, yet it flows 780 cfm as opposed to 750cfm.  The 30 cfm difference in flow capacity is caused by a more restrictive booster, which in turn offers a stronger signal."
 
Also, the 3310-1 is listed by Holley as a 4150 model and the 3310-2, 3310-3, and 3310-4 are 4160 models.  The 3310-1 has metering blocks in the primary and secondary bowls to allow jet changes on both sides; whereas the 3310-2, -3, -4 have a metering block in the primary fuel and a metering plate in the secondary- which does not allow jet changes.
 
My two cents on which carb to use is the 3310.  I personally own a 73 Chevy C-10 with factory 454, th400 combo.  It is stock except that I have changed over to HEI, added an Edelbrock Performer (oval port) and run a Holley 3310-1.  I have great throttle response and get "decent" mileage; with 3.08 gear in town I get 10-12 mpg and 15+ highway.  Once I have enough Benjamins I'll be looking for a 70 Chevelle to transplant the motor and trans into.

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