Good morning all

I've been reading posts for about a month and after current 
developments I've decided to make an introduction.  Our 11 year old 
son Adam was diagnosed with CML in March of this year.  He was put 
on 400mg of Gleevac and seemed to be responding quite well.  His 
counts came down and he became FISH negative.  We were expecting 
molecular remission any day (any mother's wish) when we got a call 
telling us his FISH had once again become positive.  After another 
test to make sure the machine hadn't malfunctioned we knew that he 
was showing signs of resistance.  His FISH went from negative to 
0.5% to 1.0%  They have increased his dosage to 800mg and as of 
yesterday have noticed a few swollen lymph nodes under his arm.  We 
have been advised to start the transplant procedure and will be 
having our "intake" meeting next week.  Adam's brother is not a 
match and there have been two matches (both 6/6) found on the 
registry.  We live in Calgary, Alberta, Canada and our transplant 
center will be the Alberta Children's Hospital.  I've asked about 
the trial drugs and have been told that they are not available to us 
(because of where we live or because he's a pediatric patient, I'm 
not sure).  Our doctor tells us that the procedure can be stopped at 
any time (pre-condinioning of course) but we're currently looking at 
late January, early February.  I have great confidence in our doctor 
I'm just extremely frightened about our son's future.  Can someone 
tell me what the swollen lymph nodes mean?  Your postings have been 
a great comfort and an incredible source if information.  Until I 
read the postings regarding the nose problems I just assumed my son 
was being a typical boy.  Our doctor suggested using vitamin E from 
a capsule.  Anyway, sorry to be so long winded.  May God Bless you 
all and keep you strengthened.

Suzanne

GOD IS WITH US WHERE EVER WE ARE CALLED TO GO





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