Thanks Cheryl Anne,
This helps me understand why my onc was only semi happy about my 
results, though I was 0 PH+ and PCR at .4%, my myloid blasts had only 
dropped from 3% to 2% after 6 mths.  That's what he wanted to see at 
0%, he had said that once blasts are at zero there is longer 
remission hold AND less chance of mutation.  
Brenda


--- In [email protected], "Cheryl-Anne Simoneau" 
<[EMAIL PROTECTED]> wrote:
> Blast count and cytogenetics correlate and are useful parameters 
for the
> evaluation of different phases in chronic myeloid leukemia.
> 
> Bacher U, Kern W, Schnittger S, Hiddemann W, Schoch C, Haferlach T.
> 
> Staging of chronic myeloid leukemia (CML) phases is based on
> cytomorphological criteria that vary considerably between different 
staging
> systems. Thus, staging of CML is heterogeneous and causes problems 
with
> respect to the comparison of therapeutical strategies and clinical 
outcome.
> We evaluated 59 patients with CML in different stages of the 
disease. In
> order to define which cytomorphological parameters correlate with
> cytogenetics we investigated cytomorphology and cytogenetics in 
parallel in
> all cases. As a result, bone marrow blast count demonstrated a 
highly
> significant correlation with the respective cytogenetic results of 
the
> patients and was clearly linked to the frequency and complexity of 
clonal
> evolution. We therefore propose to focus staging systems of CML on 
the
> correlation of the percentage of bone marrow blasts and the 
cytogenetic
> results.





New! Sign up for local CML support group meetings in your local community at 
http://cml.meetup.com

Apply for Commercial Real Estate loans online and submit your deal to dozens of 
hungry lenders in just minutes. Loan programs for all types of business and 
commercial real estate. Apply anytime at http://realestatezoo.com 

CML (Chronic Myelogenous Leukemia Support List) 
---------------------------------
Part Of CMLHope.Com
An International Community Of CML Patients
For more information: http://cmlhope.com 

Post Message: [email protected] 
Subscribe:  [EMAIL PROTECTED] 
Unsubscribe:  [EMAIL PROTECTED] 
Change To No Mail/Web: [EMAIL PROTECTED] 
Change To Digest: [EMAIL PROTECTED] 
Change To Email: [EMAIL PROTECTED] 
List Help: [EMAIL PROTECTED]  
CML Group Web Site http://groups.yahoo.com/group/CML 
 
Yahoo! Groups Links

<*> To visit your group on the web, go to:
    http://groups.yahoo.com/group/CML/

<*> To unsubscribe from this group, send an email to:
    [EMAIL PROTECTED]

<*> Your use of Yahoo! Groups is subject to:
    http://docs.yahoo.com/info/terms/
 



Reply via email to