[CML] Information on Trisomy 8

[James Beck]

Hi To All, Here is some information that I found while searching on Google.  I searched the word Trisomy 8...and this was the result.  Hope this helps.     Regards, Jim Beck - PA dx 8/2001 gleevec 600mg   +8 or trisomy 8 Clinics and Pathology Disease chronic myelogenous leukaemia (CML) Epidemiology +8 is one of the major anomalies additional to the t(9;22), with i(17q), + der(22), before +19; found as a unique additional anomaly in 10%, with other in 25% of CML cases with clonal evolution; these additional anomalies may be present at the diagnosis of CML (in 10%, possibly with unfavourable significance), or may appear during course of the disease, they do not indicate the imminence of a blast crisis, although they also frequently emerge at the time of acute transformation; +8 is more often found in the myeloid than in the lymphoid blast crisis. Prognosis +8 has apparently no prognostic significance in CML Check the site shown below....seems to have a lot of other information... ( looks like a site originating from France)   Web Site - http://www.infobiogen.fr/services/chromcancer/Anomalies/tri8ID1017.html     New! Sign up for local CML support group meetings in your local community at http://cml.meetup.com Apply for Commercial Real Estate loans online and submit your deal to dozens of hungry lenders in just minutes. Loan programs for all types of business and commercial real estate. Apply anytime at http://realestatezoo.com CML (Chronic Myelogenous Leukemia Support List) --------------------------------- Part Of CMLHope.Com An International Community Of CML Patients For more information: http://cmlhope.com Post Message: cml@yahoogroups.com Subscribe:  [EMAIL PROTECTED] Unsubscribe:  [EMAIL PROTECTED] Change To No Mail/Web: [EMAIL PROTECTED] Change To Digest: [EMAIL PROTECTED] Change To Email: [EMAIL PROTECTED] List Help: [EMAIL PROTECTED]  CML Group Web Site http://groups.yahoo.com/group/CML Yahoo! Groups Links To visit your group on the web, go to: http://groups.yahoo.com/group/CML/   To unsubscribe from this group, send an email to: [EMAIL PROTECTED]   Your use of Yahoo! Groups is subject to the Yahoo! Terms of Service.