Hi Carl and sorry to hear about troubles. I wish you the best of everything. Hang in there; keep fighting. Blessings, Jeanie<3 In a message dated 2/21/2008 9:59:28 P.M. Pacific Standard Time, [EMAIL PROTECTED] writes:
Dear Group: I have had CML for five years and have recently developed the G250E mutation which, I understand, is sensitive to both dasatinib and nilotinib. I am now on 800 mg. of imatinib but PCR has gradually risen over the past months from neglible to .5% PCR from the bone marrow and .3% PCR from peripheral blood. FISH is 0/500 down from 2/500 about a month ago. Cytogenetics are pending. My doc at MSKCC, who is considering switching me to dasatinib, says the response data for patients for both these drugs is rather sparse. Does anyone have info. or data on the G250E mutation and which drug is most effective. It looks as if Gleevec and I will be getting a divorce. Many thanks, Carl Davies **************Ideas to please picky eaters. Watch video on AOL Living. (http://living.aol.com/video/how-to-please-your-picky-eater/rachel-campos-duffy/ 2050827?NCID=aolcmp00300000002598) --~--~---------~--~----~------------~-------~--~----~ [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [EMAIL PROTECTED] For more options, visit this group at http://groups.google.com/group/CMLHope -~----------~----~----~----~------~----~------~--~---
