Joyce,

I have had to go off of Sprycel several times due to pleural effusion,
which typically clears up for me within a week or so of being off of meds.

I am currently fighting one again now with bronchitis! lol

I do not know whether you husband has an effusion around his lungs or his
heart, but here is some info on pleural effusion:

What is Pleural Effusion and What Does it Feel Like?
<http://www.leukemiasurvivor.co/2013/09/what-is-pleural-effusion-and-what-does.html>

Hope this helps!
Michele

On Mon, Sep 8, 2014 at 9:33 PM, Joyce Mesnarich <[email protected]> wrote:

> Have been reading the reports of various CMLers having side effects from
> the various TKIs.  Jut wanted to weigh in with my husband's latest
> experiences.  He was short-winded and family doc ordered a chest X-ray
> which revealed some effusion.  We reported this to Dr Talpaz (his CML
> specialist) and Dr T wanted him to have an echogram which we were able to
> do locally with his regular cardiologist.  Dr T said to quit taking Sprycel
> immediately and not to continue until he and the cardio conferred.  As of
> now, he will have another echo in a week to see if there is any change one
> way or the other.  He has an appointment with Dr Talpaz in Michigan the
> middle of October and it sounds like they are going to have him stay off
> Sprycel until at least then.  It's kind of scary being off the medication
> that you know is saving your life.  But Dr T is not concerned.  Don't know
> where this is going next.  All part of the journey.  Continue to pray for
> all the warriors out there.
> Thank you for your input.
>        Joyce in IL
>
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