>From what I have read here and elsewhere, it seems to me that Sprycel will 
definitely cause PE, it is only a question of WHEN, not IF.
For this reason, I have avoided this drug like the plague. Currently, 
Tasigna is keeping at a 3.2 log reduction, which is a sub-optimal response.
My doctor keeps telling me, that PE is "easily controlled with diuretics". 
However, I have not heard this from anybody else.
Does anyone here know anything about the use of diuretics to control PE?

Peter

On Monday, September 8, 2014 11:33:33 PM UTC-4, grammie wrote:
>
> Have been reading the reports of various CMLers having side effects from 
> the various TKIs.  Jut wanted to weigh in with my husband's latest 
> experiences.  He was short-winded and family doc ordered a chest X-ray 
> which revealed some effusion.  We reported this to Dr Talpaz (his CML 
> specialist) and Dr T wanted him to have an echogram which we were able to 
> do locally with his regular cardiologist.  Dr T said to quit taking Sprycel 
> immediately and not to continue until he and the cardio conferred.  As of 
> now, he will have another echo in a week to see if there is any change one 
> way or the other.  He has an appointment with Dr Talpaz in Michigan the 
> middle of October and it sounds like they are going to have him stay off 
> Sprycel until at least then.  It's kind of scary being off the medication 
> that you know is saving your life.  But Dr T is not concerned.  Don't know 
> where this is going next.  All part of the journey.  Continue to pray for 
> all the warriors out there. 
> Thank you for your input. 
>        Joyce in IL

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