Hi, this is Choi from South Korea. One of my CML friends had some problems and I just wonder who had a similar experience.
He was diagnosed with CML chronic phase on july 2012 and started Gleevec 400mg for 16 months and switched to Sprycel due to E355G mutation. At that time his PCR was 1.89. He started Sprycel and E355G mutaiton was disappered. He was on Sprycel for 12 months. He developed pleural effusions after 12 months of Sprycel at that time his dose was 100mg. His doctor stopped Sprycel for 2 weeks and restarted Sprycel 80mg for 3 months. Once again he developed pleural effusions so he was off Sprycel for 4 weeks and restarted Sprycel 60mg until now and still had minor pleural effusions. PCR count was 0.37, 0.47, 0.45 and never drop to under 0.1% so his doctor was considering to switch to other drugs but hesitated to switch because of he had E355G mutation. Is there any one who had a similar experience? Choi. -- -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope --- You received this message because you are subscribed to the Google Groups "CMLHope" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. For more options, visit https://groups.google.com/d/optout.
