Hi Joyce: if you go to drugs.com and type in name omacetaxine is well explained. It requires an injection twice a day, which I did. I was on it about two years. I have been 100% Phillies until I started ponatinib and this drug reduced my phone Phillies to about 50%. I am very sensitive to ponatinib as it is a strong medication. There are some issues with side effects with the heart. Right now I am off the drug for a three week period and will probably go on one pill a week when get a cbc. My counts are WB 3.5, platelets 17 and red blood 116. I am sorry your husband is involved with this but at least the drugs are pretty good. I have had cml for 15 and one half years. Cheers John B
Sent from my iPad > On Jun 9, 2015, at 11:00 PM, Joyce Mesnarich <joy...@htc.net> wrote: > > John, > When you were on sprycel did you get to PCRU? My husband was on sprycel for > 3 years and then, just as you, had to go off because of pleural effusion. He > was undetectable for 2 years and lost his PCRU in 2 months. He is now on > bosulif.....first 100 mg which was not working.....then on 200 mg which he > will find out in July if it is doing anything good. > I am not familiar with omacetaxine. Can you enlighten us on what it is and > what it is for? > Wish you well on ponatinib. > Joyce in IL > > >> On Jun 9, 2015, at 6:31 AM, John Barrons wrote: >> >> Hi Choi I was on sprycel and to go off it because of pleural effusion. I >> then went on omacetaxine for a couple of years and finally am on ponatinib. >> I only take normally one pill a week it is a strong drug so I am off it for >> three weeks. John B >> >> >> >> >> >> >> >> >> >> >> Sent from my iPad >> >>> On Jun 9, 2015, at 6:47 AM, Choi <saehyun...@naver.com> wrote: >>> >>> Hi, this is Choi from South Korea. One of my CML friends had some problems >>> and I just wonder who had a similar experience. >>> >>> He was diagnosed with CML chronic phase on july 2012 and started Gleevec >>> 400mg for 16 months and switched to Sprycel due to E355G mutation. >>> At that time his PCR was 1.89. He started Sprycel and E355G mutaiton was >>> disappered. He was on Sprycel for 12 months. >>> He developed pleural effusions after 12 months of Sprycel at that time his >>> dose was 100mg. His doctor stopped Sprycel for 2 weeks and restarted >>> Sprycel 80mg for 3 months. >>> Once again he developed pleural effusions so he was off Sprycel for 4 weeks >>> and restarted Sprycel 60mg until now and still had minor pleural effusions. >>> PCR count was 0.37, 0.47, 0.45 and never drop to under 0.1% so his doctor >>> was considering to switch to other drugs but hesitated to switch because of >>> he had E355G mutation. >>> Is there any one who had a similar experience? >>> >>> Choi. >>> >>> -- >>> -- >>> [CMLHope] >>> A support group of http://cmlhope.com >>> ------------------------------------------------- >>> >>> You received this message because you are subscribed to the Google Groups >>> "CMLHope" group. >>> To post to this group, send email to CMLHope@googlegroups.com >>> To unsubscribe from this group, send email to >>> cmlhope-unsubscr...@googlegroups.com >>> For more options, visit this group at http://groups.google.com/group/CMLHope >>> --- >>> You received this message because you are subscribed to the Google Groups >>> "CMLHope" group. >>> To unsubscribe from this group and stop receiving emails from it, send an >>> email to cmlhope+unsubscr...@googlegroups.com. >>> For more options, visit https://groups.google.com/d/optout. >> >> >> -- >> -- >> [CMLHope] >> A support group of http://cmlhope.com >> ------------------------------------------------- >> >> You received this message because you are subscribed to the Google Groups >> "CMLHope" group. >> To post to this group, send email to CMLHope@googlegroups.com >> To unsubscribe from this group, send email to >> cmlhope-unsubscr...@googlegroups.com >> For more options, visit this group at http://groups.google.com/group/CMLHope >> --- >> You received this message because you are subscribed to the Google Groups >> "CMLHope" group. >> To unsubscribe from this group and stop receiving emails from it, send an >> email to cmlhope+unsubscr...@googlegroups.com. >> For more options, visit https://groups.google.com/d/optout. > > -- > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to CMLHope@googlegroups.com > To unsubscribe from this group, send email to > cmlhope-unsubscr...@googlegroups.com > For more options, visit this group at http://groups.google.com/group/CMLHope > --- > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to cmlhope+unsubscr...@googlegroups.com. > For more options, visit https://groups.google.com/d/optout. -- -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to CMLHope@googlegroups.com To unsubscribe from this group, send email to cmlhope-unsubscr...@googlegroups.com For more options, visit this group at http://groups.google.com/group/CMLHope --- You received this message because you are subscribed to the Google Groups "CMLHope" group. To unsubscribe from this group and stop receiving emails from it, send an email to cmlhope+unsubscr...@googlegroups.com. For more options, visit https://groups.google.com/d/optout.
