Hello All,
I am new to the group. Hope you can help answer my question. 
History: I was diagnosed CML  in 2001. After 2-3 years On gleevec 400mg, I was 
in major molecular response and then undetectable (0.000) for around > 10 years 
or so..
Now suddenly last month in my last Bcd-abl it showed that I am 
0.018 and repeating it after a month, it's 0.021 so little bit higher than last 
one..
Is it considered gleevec resistance? Where I need to switch?

BTW:
I missed 3 doses or so in the last month and that is 
Where it (Bcd-abl by PCR) came 0.018 but not sure if 3 days can be that 
critical. Also I don't take medicine at the same time sometimes with breakfast 
sometimes with late lunch.  Can that suddenly change the response? 

Any thoughts or similar situation insight is much appreciated..
Thanks
Raj

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