Thank you for the note. Regular blood work is ok. My onco thinks it's a blip. Keeping figures crossed!! Good luck and thanks for the reply..
Best Regards, Rakesh Doshi (513) 205-7469 > On May 21, 2016, at 10:27 AM, 'Icandoallttc' via CMLHope > <[email protected]> wrote: > > Hi Raj > I was in Gleevec for 5 years and then it quit working for me. My platelets > and WBC shot up really high. I was put in Tasigna but it never worked for me. > Then I went in sprycel and it worked for a few years and put me in remission. > It quit working and again my platelets and WBC shot up. I'm on Ponatinib now > and doing really good in it. Make sure not to do proton pump inhibitors > while on tkis. > How are your regular blood results. > Good luck. > > > My Motto: Faith and Pills❤️ > With 💗Jeanie 🐟🐟18,s Chi > Dx 1/2004. CML Leukemia > Started Gleevec 2/2004 > Started Tasigna 9/2009 > Started Sprycel 11/2009 > Started Ponatinib January 2015 > Dr Balducci Moffitt Cancer Center > >> On May 19, 2016, at 12:10 AM, Richard H <[email protected]> wrote: >> >> When I have never had a long response of 0.000 response. I was off Gleevec >> for 6 1/2 years, when had to go back on Gleevec. I have actually reduced >> Gleevec to 300mg because CML likes to to work on my blood. I run from 0.000 >> to 0.00.3 on my Bcd-abl every 3-6 months. It is not being called >> resistance, but my controlled CML world seems to stay very controlled at >> this point. So if they put you on Gleevec again it should be Okay. When I >> went back on 400 mg of Gleevec it started decreasing my hemg. and I was >> headed for more transfusions. When my ONC lowered it to 300mg we could get >> Procrit to build my hemg so that I don't have to have a transfusion. I was >> diagnosed in 2002. >> >> Keep a positive mind and know that will help to pass this bump in the road. >> Gleevec has the most history for our ONC to work with and that is the reason >> I have remained on Gleevec, Other health problems makes the newer drugs >> make changing to them not the best choice. >> >> Richard H. >> >>> On Wednesday, May 18, 2016 at 8:05:48 PM UTC-5, Raj wrote: >>> Hello All, >>> I am new to the group. Hope you can help answer my question. >>> History: I was diagnosed CML in 2001. After 2-3 years On gleevec 400mg, I >>> was in major molecular response and then undetectable (0.000) for around > >>> 10 years or so.. >>> Now suddenly last month in my last Bcd-abl it showed that I am >>> 0.018 and repeating it after a month, it's 0.021 so little bit higher than >>> last one.. >>> Is it considered gleevec resistance? Where I need to switch? >>> BTW: >>> I missed 3 doses or so in the last month and that is >>> Where it (Bcd-abl by PCR) came 0.018 but not sure if 3 days can be that >>> critical. Also I don't take medicine at the same time sometimes with >>> breakfast sometimes with late lunch. Can that suddenly change the response? >>> >>> Any thoughts or similar situation insight is much appreciated.. >>> Thanks >>> Raj >>> >> >> -- >> -- >> [CMLHope] >> A support group of http://cmlhope.com >> ------------------------------------------------- >> >> You received this message because you are subscribed to the Google Groups >> "CMLHope" group. >> To post to this group, send email to [email protected] >> To unsubscribe from this group, send email to >> [email protected] >> For more options, visit this group at http://groups.google.com/group/CMLHope >> --- >> You received this message because you are subscribed to the Google Groups >> "CMLHope" group. >> To unsubscribe from this group and stop receiving emails from it, send an >> email to [email protected]. >> For more options, visit https://groups.google.com/d/optout. > -- > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to [email protected] > To unsubscribe from this group, send email to > [email protected] > For more options, visit this group at http://groups.google.com/group/CMLHope > --- > You received this message because you are subscribed to a topic in the Google > Groups "CMLHope" group. > To unsubscribe from this topic, visit > https://groups.google.com/d/topic/cmlhope/MNT3rmp0wDI/unsubscribe. > To unsubscribe from this group and all its topics, send an email to > [email protected]. > For more options, visit https://groups.google.com/d/optout. -- -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope --- You received this message because you are subscribed to the Google Groups "CMLHope" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. For more options, visit https://groups.google.com/d/optout.
