Yes Ragavan, I too had the same problem. I can only take a small dose of Dasatanib because I get the plural effusions and swelling around the heart from the medication. It is a known side effect that can creep up any time. Many patients do just fine on a very specific dose, if they raise it, it can cause this problem you are describing. These TKi's can also impact the heart in other ways, but I strongly suggest that you see your doc and ask for a cardio-oncologist to help you. Those are cardiologists that specialize in how these cancer drugs impact the heart. The standard for sprycel patients, is that we do an echo cardiogram at least twice a year to make sure the heart is pumping well and there is no sign of PE etc.
I do not know when you next appointment is scheduled, but I would not wait to long to get in to see your doc. It could be from the medication increase, it could be something else, but knowing is important, because swift action is needed so you do not under attend a potential big problem. If you cannot take a deep breath, and this is NOT your baseline, then that's a big problem. Sometimes we must push our doctors and fight to advocate for ourselves, to get the right testing, etc... If your doctor chose to push up your dose based upon your BCR-ABl testing, then talk with them. There are several TKI's out there and two in trials... Sending you strength, and peace....go see your doc!!! Worried about you in Chicago.. Love to all, 18's Beth. -----Original Message----- From: Joyce Mesnarich <[email protected]> To: cmlhope <[email protected]> Sent: Sat, Jul 28, 2018 3:22 pm Subject: Re: [CMLHope] Breathing Difficulties [Dasatinib] Gopalsamy, I suggest you make an appointment with your CML specialist right now. My husband had the same experience with Dasatinib. Turned out it had caused fluid around his heart. Please get this checked out immediately. Joyce in Southern Illinois (USA) On Jul 28, 2018, at 8:26 AM, Gopalsamy Ragavan <[email protected]> wrote: I was taking 50mg Dasatinib per day. An year back it was increased to 75mg. For the last few months breathing difficulty is keep increasing. I am not able to take full breath. It is always half breath. I will discuss with my doctor in the coming visit. Did anybody else face the same problem? How did you handle? Please help. thanks, Ragavan -- -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope --- You received this message because you are subscribed to the Google Groups "CMLHope" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. For more options, visit https://groups.google.com/d/optout. -- -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope --- You received this message because you are subscribed to the Google Groups "CMLHope" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. For more options, visit https://groups.google.com/d/optout. -- -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to [email protected] To unsubscribe from this group, send email to [email protected] For more options, visit this group at http://groups.google.com/group/CMLHope --- You received this message because you are subscribed to the Google Groups "CMLHope" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. For more options, visit https://groups.google.com/d/optout.
