On 01/10/14 16:32, Doeke Hekstra wrote:
As a novice to making electron density difference maps, I am curious about the algorithm underlying the “make a difference map” option in Coot. My impression is that the subtraction occurs in real space rather than at the level of structure factors.
Yes.
Given the remark in the Coot manual that this can be done regardless of differences in grid parameters I would assume Coot interpolates to a finer underlying grid.
Yes.
Are my inferences correct?
Yes.
A real-space subtraction would be quite interesting, since I am comparing data sets that are/can be processed in different space groups.
That was the plan. Paul.
