Hi Ian,

Thanks a lot for your answers. They are very informative. I am afraid that
I was looking in the wrong direction to figure out what I seek. So, I am
reforming my question; I am trying to figure out whether the relation
between the RMSD and the e/A^3 is linear or not. Therefore, I was looking
for how does COOT calculate the RMSD, hoping to find the relation between
RMSD and e/A^3. If you could refer to me a reference that is related to
this, it will be great.
One more question, you mentioned that " it shouldn't be called sigma
because it's not an uncertainty ", so when we say, for example, this map is
contoured at 3 sigma, this is a wrong statement?

Cheers,

On Thu, Apr 19, 2018 at 2:57 PM, Ian Tickle <[email protected]> wrote:

>
> Hi, first maps are produced by Refmac, not Coot, and second it shouldn't
> be called sigma because it's not an uncertainty, it's a root-mean-square
> deviation from the mean.  The equation for the RMSD can be found in any
> basic text on statistics, e.g. just type 'RMSD' in Wikipedia.
>
> Cheers
>
> -- Ian
>
>
> On 19 April 2018 at 13:20, Mohamed Ibrahim <[email protected]>
> wrote:
>
>> Dear COOT users,
>>
>> Do you know how to extract the equations that COOT uses for generating
>> the maps and calculating the sigma values?
>>
>> Best regards,
>> Mohamed
>>
>> --
>> ​
>> --
>> *​----------------------------------*
>> *Mohamed Ibrahim              *
>>
>> *Humboldt University           *
>> *Berlin, Germany                  *
>>
>> *Tel: +49 30 209347931  *
>>
>
>


-- 
​
-- 
*​----------------------------------*
*Mohamed Ibrahim              *

*Humboldt University           *
*Berlin, Germany                  *

*Tel: +49 30 209347931  *

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