The program dottup (and other dotplot tools) takes the two sequence given and displays a dotplot. It would be useful if you could give it the option to reverse complement one of the sequences then perform a dotplot. I was comparing a mRNA with a genomic sequence and wasn't seeing the similarity between the sequences. Then I releazied I needed to rev-comp the mRNA and it showed up fine. Of course, one can do this using revseq, but to have dottup do it for you would be even better. Ryan
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