On Wed, Aug 14, 2013 at 11:57:59PM -0400, John Clark wrote: > Russell Standish <[email protected]> wrote: > > > > >>>[The central dogma of molecular biology] deals with the detailed > >>> states that such information cannot be transferred back from protein to > >>> either protein or nucleic acid. > >>> > >>> > >> >> I know of no example of a change in a protein making a systematic > >> repeatable change (as opposed to a random mutation) in the sequence of > >> bases in DNA that are passed onto the next generation. > >> > > > > > Epigenetic information is expressed by the presence or absence of > > methylation of the bases, not the sequence. > > > > A keen grasp of the obvious. So because information is not being > transferred from proteins to the base sequence of DNA I take it that you > are retracting your statement that epigenesis contradicts the central > dogma, not that it would matter because that is about molecular biology and > we're talking about Darwin and Evolution.
No - because the central dogma is about information being passed from the phenotype to the genotype. Even Crick's more restricted version doesn't mention nucleotide sequence - just information of the nucleic acid, and methylation of nucleotides is exactly that. > By the way, after the discovery > of prions a couple of decades ago we knew that sometimes hereditary > information can move from protein to protein and bypass DNA, so the central > dogma is not 100% true, just 98 or 99% true. > Yes, of course. Like pretty much all dogmas. And it took a generation of scientists before prion theory was accepted, another characteristic of a dogma. -- ---------------------------------------------------------------------------- Prof Russell Standish Phone 0425 253119 (mobile) Principal, High Performance Coders Visiting Professor of Mathematics [email protected] University of New South Wales http://www.hpcoders.com.au ---------------------------------------------------------------------------- -- You received this message because you are subscribed to the Google Groups "Everything List" group. To unsubscribe from this group and stop receiving emails from it, send an email to [email protected]. To post to this group, send email to [email protected]. Visit this group at http://groups.google.com/group/everything-list. For more options, visit https://groups.google.com/groups/opt_out.
