yikes... Dr. Daley may not be familiar with how epogen works, Caroline-- how long ago did Monkee get an epogen? It usually takes two to three weeks for epogen to show any effect --the meantime, his PCV will continue to go down.. but you don't know yet if he was only give a week ago,
again, since he is not sure whether epogen works or not, I would so very much recommend that you switch to aranesp from epogen.. again 30% to 50% of cats will develop antibody, once it does, epogen will destroy human erytheipoten (produced by epogen) as well as natural erytheiopoeitn that Monkee produces on his own, and his anemia will become more severe, and it will take two months to a year before antibody reactions goes away from his body --the meantime, you have to give him multiple transfusion to tie his life.. I am advising this to you, that's exactly what happened to ayumi and I regeret that I did not use aranesep -- aranesp works a similar way to epogen, but much less possibility of him getting antibody reactions - lots of vet schools now uses aranesp over epogen due to the risk mentioned earilier. This antibody reaction can be fatal. Epogen needs to be injected in cats three times a week initially and you need to monitor his PCV weekly and also his BP, epogen will cause high BP in cats (hypertension) and will cause a cat to be blind.. my hannibal became blind after one week therapy of epogen due to high BP -- make sure you check his BP now and regularly during epogen therapy, anything over 150 to 160 is high, and he needs to be on norvasc to control hypertension. and pay attention to his pupils to make sure that it does not look dilated.. if it does, you need to take him to emergency to get norvasc, as there is a chance to reversre blindess if you catch it with in 24 to 48 hours or so. thank you. Hideyo ----- Original Message ----- From: Caroline Kaufmann<mailto:[EMAIL PROTECTED]> To: [email protected]<mailto:[email protected]> Sent: Friday, June 29, 2007 10:32 AM Subject: Re: To Belinda: Re: Anemia Issues Monkee only had one week's treatment of Epogen. Dr. Daley didn't say anything about continuing Epogen or trying a second dose. When I asked on Tues. if the Epogen helped him at all, she said no, because his red blood cell count was actually lower. So, I don't know if we should try it again (meaning, if I should ASK for Monkee to be able to try it again)? I was also not instructed as to whether or not we should re-start his 7-days-on of Interferon, which would start today? I put a call into Dr. Daley yesterday about that and haven't heard back yet. ---------------------------------------------------------------------------- From: "HIDEYO YAMAMOTO" <[EMAIL PROTECTED]> Reply-To: [email protected] To: <[email protected]> Subject: Re: To Belinda: Re: Anemia Issues Date: Fri, 29 Jun 2007 09:03:12 -0600 I know that it's not very common - but I did hear from two other people from anemia list who responded to epogen who had non-regenerative anemia but who was not a CRF kitty -- I have my kitty, ayumi who has non regenerative anemia with unknown cause is also suffering from anemia -- she was coping with anemial pretty well, until I started using epogen (though it seems to have worked for a tiny bit --), then she might have developed antibody reaction as her anemia got worse than before she started treatment -- so I stopped epogen therapy completely and she got her first transfusion -- my hope is that, after several weeks, antibody reaction will go away and her PCV will go back to where it was before the therapy... I do however, recommend due to antibody reaction possibility (up to 30% to 50% of cats in some study), using aranesp over epogen... and sometimes, it works among kitties who developed antiboy to epogen, and antibody reaction % is much less than epogen.. if I had researched a bit more regarding the real % of epogen, I would probably have used aranesp over epogen in a heartbeat.. as I feel that she never really got benefit of epogen, but it may have harmed her more -- aranesp is a bit more expensive.. but I am considering using it for ayumi soon. ----- Original Message ----- From: wendy<mailto:[EMAIL PROTECTED]> To: [email protected]<mailto:[email protected]> Sent: Friday, June 29, 2007 8:46 AM Subject: To Belinda: Re: Anemia Issues Hi Belinda, In response to your post below, I felt the need to clarify for Caroline's sake. Bailey's situation should be considered a miracle in my book. As we have seen too many times here, most cats do not respond as Bailey did with that type of anemia; it claims the lives of many. While I do not wish to play a part in taking away Caroline's hope, I also want to be completely upfront about non-regenerative anemia. It can be reversed, but not usually. I should have made this statement earlier. So That being said, it may be wise to keep her kitty on Epogen considering Bailey's case, as we never know when a situation might be reversed. Respectfully, Wendy --- Belinda <[EMAIL PROTECTED]<mailto:[EMAIL PROTECTED]>> wrote: > Everytime I hear this I post this, Bailey's anemia > was non regenerative > and we DID reverse it. > > > and it is not a good anemia to have. 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