Hi Sherri
Yes, I do see something positive. As I mentioned in my previous email, the
reticulocyte count ("retic") is a count showing immature red cells. Normally,
red cells are not pushed out of the bone marrow into the general circulation of
the blood, until they are mature, though a small percentage may be in the
bloodstream at all times. The presence of an elevated number of reticulocytes
says to me that the bone marrow is starting to create new red cells and because
the body is short of red cells (anemic), the bone marrow is pushing out more of
the red cells in their immature form, into the circulation. This is the body
trying to correct the anemia.
You definitely need the previous results though, to identify if you are moving
in the right direction on the other parameters.
Amani
From: Felvtalk [mailto:[email protected]] On Behalf Of Sherri
Godschalk
Sent: August-26-16 5:34 PM
To: [email protected]
Subject: Re: [Felvtalk] Bogie's First 5 days on Stanozolol
Amani,
Thanks for all the valuable information. It actually calms me.
He has a lab in house and these were the results from this week. (I don't have
any from the prior visits to the other vet, but the new vet does)
RBC 2.43 M/ul 6.65-12.2 LOW
HCT 15.3 % 30.3-52.3 LOW
HGB 5.3 g/dL 9.8-16.2 LOW
MCV 62.6 fl 35.9-53.1 HIGH
MCH 21.8 pg 11.8-17.3 HIGH
RETIC 61.5 K/ul 3.0-50.0 HIGH
LYM 7.75 K/uL 0.92-6.88 HIGH
MONO 1.58 K/uL 0.05-0.67 HIGH
EOS 0.10 K/uL 0.17-1.57 LOW
BASO 0.00 K/uL 0.01-.26 LOW
PLT 50 K/uL 151-600 LOW
I haven't got the chance to research what all of this means. There were several
other levels on this sheet that were all within range. Do you see ANYTHING
positive in these results? The first 6 look very bad to me.
Thanks again for writing.
From: Felvtalk
<[email protected]<mailto:[email protected]>>
on behalf of Amani Oakley
<[email protected]<mailto:[email protected]>>
Reply-To: <[email protected]<mailto:[email protected]>>
Date: Friday, August 26, 2016 at 3:29 PM
To: "[email protected]<mailto:[email protected]>"
<[email protected]<mailto:[email protected]>>
Subject: Re: [Felvtalk] Bogie's First 5 days on Stanozolol
Sherri
Don't be disappointed. The key is that the haematocrit is starting to rise and
is not going down any further. Remember how few days the drug has had to work.
It is literally having to go into bone marrow and turn back on progenitor cells
in the bone marrow that have been infiltrated by the FeLV virus, and are
therefore destroyed or inactive. Also, did he do a reticulocyte count? That
should hopefully also start going up because those are one of the immature
forms of the red cells. Another is nucleated red blood cells. At maturity, the
red cells lose the nucleus (except in birds and maybe reptiles). However, the
instrument used to count the red cells cannot differentiate a nucleated red
cell from a white cell (which will have a nucleus) so unless there is a manual
count done, the automated instrument results may count any nucleated red cells
as white cells. This isn't too critical, but it will not show you whether any
of these immature red cell forms are developing.
Also, while the haematocrit is important, you should also look at the platelet
count (which, I remember correctly, was low for Bogie) and the white cell
counts. I found that the Winstrol started improving all the different cell
lines, though admittedly, it appeared that the improvement started with the red
cells.
I am not sure I agree with your vet taking Bogie off the Winstrol though,
because it is an anabolic steroid and is literally rebuilding bone, muscle,
etc. With a debilitated cat, I think you've got to keep them on for a long
while. However, your vet has been helpful and more progressive than most, so .
. .
Amani
From: Felvtalk [mailto:[email protected]] On Behalf Of Sherri
Godschalk
Sent: August-26-16 7:03 AM
To: [email protected]<mailto:[email protected]>
Subject: Re: [Felvtalk] Bogie's First 5 days on Stanozolol
Thanks Ardy.
We had Bogeys first blood test after 7 days and her HCT was only still at 15.4.
Slight increase. She is pretty functional at this level. Still sleeping a lot.
But eats, goes up and down stairs, bats at the dogs. The vet didn't seem
surprised that it hadn't gone up more. It hadn't gone down. Considers her
"stable". He doesn't want to see her for a month to test again. He wants her to
be off of the Stanozolol for one week starting next Wed and then put her back
on it the following week for two more.
I was a bit disappointed that her blood results weren't better although I could
tell just with her energy level that she hadn't improved much. Hopefully she
just needs more time on it for it to take hold. I wish there was something more
that I could do. I feel so helpless.
Thanks for writing,
From: Felvtalk
<[email protected]<mailto:[email protected]>>
on behalf of Ardy Robertson <[email protected]<mailto:[email protected]>>
Reply-To: <[email protected]<mailto:[email protected]>>
Date: Friday, August 26, 2016 at 12:07 AM
To: <[email protected]<mailto:[email protected]>>
Subject: Re: [Felvtalk] Bogie's First 5 days on Stanozolol
Best wishes to you Sherri and to Bogie!! I do believe this drug combo
(Stanozolol and Prednisone) helped my Tigger also, it's just that I started him
on it too late. Tigger's bloodwork showed amazing improvement but I believe his
diagnosis was very late since he had tested negative as a kitten, and at age 5
years they told me he had it since kittenhood but must have been shedding the
virus when tested. I sincerely hope Bogie can benefit from this treatment since
she is younger at her diagnosis. Also very happy that you have a cooperating
vet!
Ardy
From: Felvtalk [mailto:[email protected]] On Behalf Of Amani
Oakley
Sent: Sunday, August 21, 2016 9:30 PM
To: [email protected]<mailto:[email protected]>
Subject: Re: [Felvtalk] Bogie's First 5 days on Stanozolol
Hi Sherri
I am happy to hear of your experience so far, but like you, I held my breath
for a very long time with Zander.
Please keep us all updated.
Amani
From: Felvtalk [mailto:[email protected]] On Behalf Of Sherri
Godschalk
Sent: August-21-16 10:36 PM
To: [email protected]<mailto:[email protected]>
Subject: [Felvtalk] Bogie's First 5 days on Stanozolol
I wanted to update everyone here about how this medication is affecting the
health of my FELV positive 1 year old kitten.
Bogie got her diagnosis just under 3 weeks ago. The first vet I saw tried
Prednisone and an antibiotic for 2 weeks and it did nothing for here severe
anemia. (Her only symptom) I was told at that time that there was nothing that
could help her and to just keep her comfortable as she dies.
Changed vets.
New vet...Was prescribed 2mg of Stanozolol once a day along with the Pred once
a day. This morning, Bogie got her 5th dose of Stanozolol. She appears to be
less anemic. Has more energy, sleeping less and more interested in playing and
is eating and drinking well enough on her own. Her gums are slightly more pink
as well. There hasn't been any side effects that I have seen with this
combination. Except I have to pill her twice a day but she is getting used to
that a little bit.
I don't want to speak to soon, but I believe just from how she is acting, that
this drug is helping my kitten make some red blood cells. She goes in this week
for a blood test so I will know if it is actually doing that . Today is the
happiest day we have had in the house in over a month.
I will reply to this thread to keep the group posted.
Wish us luck!
Best.
Sherri
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