Here is hope for continued good results.

---- Amani Oakley <[email protected]> wrote: 
> Hi Sherri
> 
> Yes, I do see something positive. As I mentioned in my previous email, the 
> reticulocyte count ("retic") is a count showing immature red cells. Normally, 
> red cells are not pushed out of the bone marrow into the general circulation 
> of the blood, until they are mature, though a small percentage may be in the 
> bloodstream at all times. The presence of an elevated number of reticulocytes 
> says to me that the bone marrow is starting to create new red cells and 
> because the body is short of red cells (anemic), the bone marrow is pushing 
> out more of the red cells in their immature form, into the circulation. This 
> is the body trying to correct the anemia.
> 
> You definitely need the previous results though, to identify if you are 
> moving in the right direction on the other parameters.
> 
> Amani
> 
> From: Felvtalk [mailto:[email protected]] On Behalf Of 
> Sherri Godschalk
> Sent: August-26-16 5:34 PM
> To: [email protected]
> Subject: Re: [Felvtalk] Bogie's First 5 days on Stanozolol
> 
> Amani,
> Thanks for all the valuable information. It actually calms me.
> He has a lab in house and these were the results from this week. (I don't 
> have any from the prior visits to the other vet, but the new vet does)
> RBC          2.43 M/ul   6.65-12.2    LOW
> HCT        15.3 %         30.3-52.3      LOW
> HGB         5.3 g/dL       9.8-16.2      LOW
> MCV       62.6 fl        35.9-53.1     HIGH
> MCH      21.8 pg      11.8-17.3      HIGH
> RETIC     61.5 K/ul     3.0-50.0      HIGH
> LYM        7.75 K/uL    0.92-6.88    HIGH
> MONO   1.58 K/uL    0.05-0.67    HIGH
> EOS         0.10 K/uL   0.17-1.57     LOW
> BASO      0.00 K/uL   0.01-.26       LOW
> PLT             50 K/uL   151-600       LOW
> I haven't got the chance to research what all of this means. There were 
> several other levels on this sheet that were all within range.  Do you see 
> ANYTHING positive in these results? The first 6 look very bad to me.
> Thanks again for writing.
> 
> From: Felvtalk 
> <[email protected]<mailto:[email protected]>>
>  on behalf of Amani Oakley 
> <[email protected]<mailto:[email protected]>>
> Reply-To: <[email protected]<mailto:[email protected]>>
> Date: Friday, August 26, 2016 at 3:29 PM
> To: "[email protected]<mailto:[email protected]>" 
> <[email protected]<mailto:[email protected]>>
> Subject: Re: [Felvtalk] Bogie's First 5 days on Stanozolol
> 
> Sherri
> 
> Don't be disappointed. The key is that the haematocrit is starting to rise 
> and is not going down any further. Remember how few days the drug has had to 
> work. It is literally having to go into bone marrow and turn back on 
> progenitor cells in the bone marrow that have been infiltrated by the FeLV 
> virus, and are therefore destroyed or inactive. Also, did he do a 
> reticulocyte count? That should hopefully also start going up because those 
> are one of the immature forms of the red cells. Another is nucleated red 
> blood cells. At maturity, the red cells lose the nucleus (except in birds and 
> maybe reptiles). However, the instrument used to count the red cells cannot 
> differentiate a nucleated red cell from a white cell (which will have a 
> nucleus) so unless there is a manual count done, the automated instrument 
> results may count any nucleated red cells as white cells. This isn't too 
> critical, but it will not show you whether any of these immature red cell 
> forms are developing.
> 
> Also, while the haematocrit is important, you should also look at the 
> platelet count (which, I remember correctly, was low for Bogie) and the white 
> cell counts. I found that the Winstrol started improving all the different 
> cell lines, though admittedly, it appeared that the improvement started with 
> the red cells.
> 
> I am not sure I agree with your vet taking Bogie off the Winstrol though, 
> because it is an anabolic steroid and is literally rebuilding bone, muscle, 
> etc. With a debilitated cat, I think you've got to keep them on for a long 
> while. However, your vet has been helpful and more progressive than most, so 
> . . .
> 
> Amani
> 
> From: Felvtalk [mailto:[email protected]] On Behalf Of 
> Sherri Godschalk
> Sent: August-26-16 7:03 AM
> To: [email protected]<mailto:[email protected]>
> Subject: Re: [Felvtalk] Bogie's First 5 days on Stanozolol
> 
> Thanks Ardy.
> We had Bogeys first blood test after 7 days and her HCT was only still at 
> 15.4. Slight increase. She is pretty functional at this level. Still sleeping 
> a lot. But eats, goes up and down stairs, bats at the dogs. The vet didn't 
> seem surprised that it hadn't gone up more. It hadn't gone down. Considers 
> her "stable". He doesn't want to see her for a month to test again. He wants 
> her to be off of the Stanozolol for one week starting next Wed and then put 
> her back on it the following week for two more.
> 
> I was a bit disappointed that her blood results weren't better although I 
> could tell just with her energy level that she hadn't improved much. 
> Hopefully she just needs more time on it for it to take hold. I wish there 
> was something more that I could do. I feel so helpless.
> 
> Thanks for writing,
> 
> From: Felvtalk 
> <[email protected]<mailto:[email protected]>>
>  on behalf of Ardy Robertson 
> <[email protected]<mailto:[email protected]>>
> Reply-To: <[email protected]<mailto:[email protected]>>
> Date: Friday, August 26, 2016 at 12:07 AM
> To: <[email protected]<mailto:[email protected]>>
> Subject: Re: [Felvtalk] Bogie's First 5 days on Stanozolol
> 
> Best wishes to you Sherri and to Bogie!! I do believe this drug combo 
> (Stanozolol and Prednisone) helped my Tigger also, it's just that I started 
> him on it too late. Tigger's bloodwork showed amazing improvement but I 
> believe his diagnosis was very late since he had tested negative as a kitten, 
> and at age 5 years they told me he had it since kittenhood but must have been 
> shedding the virus when tested. I sincerely hope Bogie can benefit from this 
> treatment since she is younger at her diagnosis. Also very happy that you 
> have a cooperating vet!
> 
> Ardy
> 
> 
> From: Felvtalk [mailto:[email protected]] On Behalf Of 
> Amani Oakley
> Sent: Sunday, August 21, 2016 9:30 PM
> To: [email protected]<mailto:[email protected]>
> Subject: Re: [Felvtalk] Bogie's First 5 days on Stanozolol
> 
> Hi Sherri
> 
> I am happy to hear of your experience so far, but like you, I held my breath 
> for a very long time with Zander.
> 
> Please keep us all updated.
> 
> Amani
> 
> From: Felvtalk [mailto:[email protected]] On Behalf Of 
> Sherri Godschalk
> Sent: August-21-16 10:36 PM
> To: [email protected]<mailto:[email protected]>
> Subject: [Felvtalk] Bogie's First 5 days on Stanozolol
> 
> I wanted to update everyone here about how this medication is affecting the 
> health of my FELV positive 1 year old kitten.
> 
> Bogie got her diagnosis just under 3 weeks ago. The first vet I saw tried 
> Prednisone and an antibiotic for 2 weeks and it did nothing for here severe 
> anemia. (Her only symptom) I was told at that time that there was nothing 
> that could help her and to just keep her comfortable as she dies.
> 
> Changed vets.
> 
> New vet...Was prescribed 2mg of Stanozolol once a day along with the Pred 
> once a day. This morning, Bogie got her 5th dose of Stanozolol. She appears 
> to be less anemic. Has more energy, sleeping less and more interested in 
> playing and is eating and drinking well enough on her own. Her gums are 
> slightly more pink as well. There hasn't been any side effects that I have 
> seen with this combination. Except I have to pill her twice a day but she is 
> getting used to that a little bit.
> 
> I don't want to speak to soon, but I believe just from how she is acting, 
> that this drug is helping my kitten make some red blood cells. She goes in 
> this week for a blood test so I will know if it is actually doing that . 
> Today is the happiest day we have had in the house in over a month.
> 
> I will reply to this thread to keep the group posted.
> 
> Wish us luck!
> 
> Best.
> Sherri
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