It might be, it depends on how you defined the sign of the voxel-wise threshold. If you used "abs", then it is certainly possible.
doyug Joana Braga Pereira wrote: > Dear all, > > I would like to ask you whether there should be an exact > correspondence between vertex-wise thickness and mean thickness of > clusters. > > I'll explain you my problem. > I did an analysis with 2 groups and 2 covariates. > Then i run the mri_glmfit script and found clusters of greater > thickness in controls compared to patients. > When i extracted the mean thickness of these clusters and did a two > sample t test i observed that the controls had greater thickness than > patients, however not statistically significant, even after including > in this analysis the 2 covariates. > > Is this normal? How does freesurfer uses the covariates when > performing an analysis? > > Many thanks > ------------------------------------------------------------------------ > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer -- Douglas N. Greve, Ph.D. MGH-NMR Center gr...@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
