Hi all,

First of all, Freesurfer V6 is working like a dream, my 0.7 mm
segmentations are running really well and in comparisons to hi-resrecon in
5.3 and early beta, I'm having to do fewer manual corrections!


Now for my questions,

1. I'm running mri_mcsim in order to correct for multiple comparisons via
the FS-FAST stream. I'm wondering how many iterations are advised, and how
can one check for convergence in an automatic fashion.

I've run the simulations with 1000 and 10,000 iterations on a 1mm
segmentation with the FWHM simulations at 8mm. (i.e. using mri_mcsim --o .
--base mc-z --save-iter  --surf subject lh/rh --nreps 10000 --fwhm 8) and I
can't see many differences between the two when correcting for multiple
comparisons (i.e. using cluster-sess -analysis  myanalysis -thresh 3 -cwp
.05 -s SESSION -sign pos).

2. I'm trying to find some references that detail the simulations and form
the corrections, does anyone have advice which list I can read/start off
with, as well as some key papers that use it (esp on a single subject
level). I really like this approach and It does look to circumvent (I
think...) a lot of the problems of cluster-wise corrections described with
Eklund et al. (Cluster failure paper).

Cheers,


*Dr Kevin Aquino*
Research fellow,
Sir Peter Mansfield Magnetic Resonance Center, The University of
Nottingham.

Honorary Research Fellow
School of Physics, Faculty of Science, University of Sydney

*E* kevin.aqu...@nottingham.ac.uk, aqu...@physics.usyd.edu.au | *W*
https://kevinaquino.github.io <http://www.physics.usyd.edu.au/~aquino/>

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