you can't really do permutation at the first level because the temporal autocorrelation and non-orthogonal design matrix violate the permutation assumptions.

On 5/15/17 11:23 PM, Kevin Aquino wrote:
Actually,

would would be preferable would be running a permutations test something that you describe in:

http://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg49846.html

is there an easy to run mri_glmfit-sim's permutation simulations on a single subject?
I've run through the FS-FAST pipeline

mkanalysis-sess -fsd bold -surface self rh -fwhm 4.5 -event-related -paradigm attn.par -nconditions 4 -spmhrf 0 -TR 1.9 -analysis myanalysis -per-session -refeventdur 450 -force -nuisreg moco.txt -1 -polyfit 0
mkcontrast-sess -analysis myanalysis -contrast attn -c 1 -a 2 -a 3 -c 4
selxavg3-sess -s SESSION -analysis self_attn_sm_reg.rh -no-preproc -fwhm

But mri_glmfit-sim is expecting the output from mri_glmfit

mri_glmfit-sim --glmdir . --perm 1000 3 pos --log ./selxavg3.log
>> ERROR: cannot find ./mri_glmfit.log

should I just run mri_glmfit with the appropriate flags, or is there a mri_glmfit-sim version for data that has passed through selxavg3 ?


Cheers,


*Dr Kevin Aquino*
Research fellow,
Sir Peter Mansfield Magnetic Resonance Center, The University of Nottingham.

Honorary Research Fellow
School of Physics, Faculty of Science, University of Sydney

*E* kevin.aqu...@nottingham.ac.uk <mailto:kevin.aqu...@nottingham.ac.uk>, aqu...@physics.usyd.edu.au <mailto:aqu...@physics.usyd.edu.au> | *W* *MailScanner has detected a possible fraud attempt from "www.physics.usyd.edu.au" claiming to be* https://kevinaquino.github.io <http://www.physics.usyd.edu.au/%7Eaquino/>

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On Tue, May 16, 2017 at 12:34 PM, Kevin Aquino <aqu...@physics.usyd.edu.au <mailto:aqu...@physics.usyd.edu.au>> wrote:

    Hi all,

    First of all, Freesurfer V6 is working like a dream, my 0.7 mm
    segmentations are running really well and in comparisons to
    hi-resrecon in 5.3 and early beta, I'm having to do fewer manual
    corrections!


    Now for my questions,

    1. I'm running mri_mcsim in order to correct for multiple
    comparisons via the FS-FAST stream. I'm wondering how many
    iterations are advised, and how can one check for convergence in
    an automatic fashion.

    I've run the simulations with 1000 and 10,000 iterations on a 1mm
    segmentation with the FWHM simulations at 8mm. (i.e.
    using mri_mcsim --o . --base mc-z --save-iter  --surf subject
    lh/rh --nreps 10000 --fwhm 8) and I can't see many differences
    between the two when correcting for multiple comparisons (i.e.
    using cluster-sess -analysis  myanalysis -thresh 3 -cwp .05 -s
    SESSION -sign pos).

    2. I'm trying to find some references that detail the simulations
    and form the corrections, does anyone have advice which list I can
    read/start off with, as well as some key papers that use it (esp
    on a single subject level). I really like this approach and It
    does look to circumvent (I think...) a lot of the problems of
    cluster-wise corrections described with Eklund et al. (Cluster
    failure paper).

    Cheers,


    *Dr Kevin Aquino*
    Research fellow,
    Sir Peter Mansfield Magnetic Resonance Center, The University of
    Nottingham.

    Honorary Research Fellow
    School of Physics, Faculty of Science, University of Sydney

    *E* kevin.aqu...@nottingham.ac.uk
    <mailto:kevin.aqu...@nottingham.ac.uk>, aqu...@physics.usyd.edu.au
    <mailto:aqu...@physics.usyd.edu.au> | *W* *MailScanner has
    detected a possible fraud attempt from "www.physics.usyd.edu.au"
    claiming to be* https://kevinaquino.github.io
    <http://www.physics.usyd.edu.au/%7Eaquino/>

    ----------------------------------------------

    The brain is a wonderful organ. It starts working the moment you
    get up and does not stop until you get into the office.
    -
    Robert Frost

    CRICOS 00026A
    This email plus any attachments to it are confidential. Any
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