SUVR you can. BP is a little trickier because BP estimation is a 
nonlinear operation that can be biased by noise. Probably it comes out 
similarly.


On 08/16/2017 02:50 PM, Shane Schofield wrote:
> Hi Dr Greve,
>
> On a similar note, can I use the Petsurfer on PET data that have 
> already been averaged into a single frame 3D volume instead of 4D? 
> Example, SUVR and BPND data.
>
> Thanks for your help again.
>
>
> On Tuesday, August 15, 2017, 9:09:33 AM GMT+1, Shane Schofield 
> <shane.schofi...@yahoo.com> wrote:
>
>
> Hello Dr Greve,
>
> I have ran the command and got the data from the gtm.stats.dat. 
> However, all the values are 0.001 - 0.003. Can I scale it up or show 
> the data with more precision?
>
> Thank you.
>
>
> On Monday, August 14, 2017, 9:31:38 PM GMT+1, Douglas N Greve 
> <gr...@nmr.mgh.harvard.edu> wrote:
>
>
> You will need to run gtmseg --s subject (takes an hour or so), then add
> --seg gtmseg.mgz to the cmd line
>
>
> On 08/14/2017 04:12 PM, Shane Schofield wrote:
> > Hi Dr  Greve,
> >
> > Are the settings correct to do partial volume correction of my MD 
> images?
> >
> > mri_gtmpvc --i subject/dtrecon/adc.nii.gz --reg
> > subject/dtrecon/register.lta --psf 0 --seg subject/mri/gtmseg.mgz
> > --default-seg-merge --auto-mask PSF .01 --mgx 0.25 --o
> > subject/dtrecon/adc.pvc.mgz --no-rescale
> >
> > Thank you!
> >
> >
> >
> > On Monday, August 14, 2017, 4:36:28 PM GMT+1, Douglas N Greve
> > <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote:
> >
> >
> > The mri_gtmpvc command will remove volume fraction effects. Look at the
> > PETsurfer page. Run it with --psf 0 and use the muller-gartner output.
> > The output will only be valid for gray matter
> >
> >
> > On 08/12/2017 10:55 AM, Bruce Fischl wrote:
> > > Hi Shane
> > >
> > > we do have some tools to deal with it like
> > > mri_compute_volume_fractions and mri_compute_volume_intensities, or
> > > maybe Doug's PET stuff. At the very least you should probably regress
> > > thickness out.
> > >
> > > cheers
> > > Bruce
> > >
> > > On Sat, 12 Aug 2017, Shane Schofield wrote:
> > >
> > >> Thank you both.
> > >>
> > >> How can I deal with partial volume in this case? Would it be possible
> > >> to use
> > >> the partial volume tool for PET on my MD volumes? Sorry if it is a
> > silly
> > >> idea.
> > >>
> > >> Best Wishes,
> > >> Shane
> > >>
> > >>
> > >> On Friday, August 11, 2017, 6:19:45 PM GMT+1, Yendiki, Anastasia
> > >> <ayend...@mgh.harvard.edu <mailto:ayend...@mgh.harvard.edu> 
> <mailto:ayend...@mgh.harvard.edu <mailto:ayend...@mgh.harvard.edu>>> 
> wrote:
> > >>
> > >>
> > >> Agreed, especially so with MD. Keep in mind that you¹re upsampling MD
> > >> from
> > >> a lower-res (diffusion) space to a higher-res (T1) space, so it
> > >> should be
> > >> smooth already, relatively to measure derived from the T1. And MD
> > varies
> > >> pretty smoothly (it¹s a mean of 3 things, after all).
> > >>
> > >> On 8/11/17, 1:11 PM, "Bruce Fischl" <fis...@nmr.mgh.harvard.edu 
> <mailto:fis...@nmr.mgh.harvard.edu>
> > <mailto:fis...@nmr.mgh.harvard.edu 
> <mailto:fis...@nmr.mgh.harvard.edu>>> wrote:
> > >>
> > >> >Hi Shane
> > >> >
> > >> >not really - it totally depends on the size of the effect you are
> > >> looking
> > >> >for. I would be *very* careful about partial volume effects though
> > >> >
> > >> >cheers
> > >> >Bruce
> > >> >On Fri,
> > >> >11 Aug 2017, Shane Schofield wrote:
> > >> >
> > >> >> Appreciate it Dr Bruce. Do you have guidelines for smoothing MD?
> > >> >>
> > >> >> Dr Yendiki, I am trying to investigate whether cortical MD can 
> be a
> > >> >>marker
> > >> >> of neurodegeneration. The idea is that during the early stages 
> of a
> > >> >>disease,
> > >> >> cellular microstructure may breakdown before cortical thinning
> > >> occurs.
> > >> >>This
> > >> >> results in "less" barriers against diffusion resulting in an
> > >> increase of
> > >> >> MD.
> > >> >>
> > >> >>
> > >> >> On Friday, August 11, 2017, 5:49:40 PM GMT+1, Bruce Fischl
> > >> >> <fis...@nmr.mgh.harvard.edu 
> <mailto:fis...@nmr.mgh.harvard.edu> <mailto:fis...@nmr.mgh.harvard.edu 
> <mailto:fis...@nmr.mgh.harvard.edu>>>
> > wrote:
> > >> >>
> > >> >>
> > >> >> Hi Shane
> > >> >>
> > >> >> you probably don't need cvs as it is more to extend the
> > surface-based
> > >> >> registration to the entire volume. Here you just need the
> > >> surface-based
> > >> >> registration I believe. Use mri_vol2surf to sample the FA onto the
> > >> >>surface.
> > >> >> After that it is identical to a thickness study
> > >> >>
> > >> >> cheers
> > >> >> Bruce
> > >> >>
> > >> >>
> > >> >>
> > >> >> On Fri, 11 Aug 2017, Shane Schofield
> > >> >> wrote:
> > >> >>
> > >> >> > Thanks Dr Yendiki.
> > >> >> >
> > >> >> > I am more interested to compare MD in grey matter regions by
> > >> putting
> > >> >>the
> > >> >> MD on the surface, and then do a glmfit type of comparisons. Is
> > >> that OK?
> > >> >> Would you recommend me
> > >> >> > to smooth the data after spatial normalisation? I have also used
> > >> the
> > >> >> mri_cvs_register as described on the tutorial.
> > >> >> >
> > >> >> >
> > >> >> > On Friday, August 11, 2017, 7:03:49 AM GMT+1, Shane Schofield
> > >> >> <shane.schofi...@yahoo.com <mailto:shane.schofi...@yahoo.com> 
> <mailto:shane.schofi...@yahoo.com <mailto:shane.schofi...@yahoo.com>>>
> > wrote:
> > >> >> >
> > >> >> >
> > >> >> > Hi DTI Experts,
> > >> >> >
> > >> >> > Is it sensible to do comparisons of MD on the cortex surface
> > like a
> > >> >>normal
> > >> >> cortical thickness comparisons between group? If the answer is
> > >> yes, are
> > >> >> there recommended on
> > >> >> > smoothing ?
> > >> >> >
> > >> >> > DT_RECON has been completed in Freesurfer.
> > >> >> >
> > >> >> > Thank you.
> > >> >> >
> > >> >> >
> > >> >> >
> > >> >> _______________________________________________
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> > --
> > Douglas N. Greve, Ph.D.
> > MGH-NMR Center
> > gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu> 
> <mailto:gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>>
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> >
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> -- 
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
> Phone Number: 617-724-2358
> Fax: 617-726-7422
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MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

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