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Hello dear all,

I use Freesurfer-Samseg for MS lesion segmentation(cross-sectional).

I use the T1 and Flair for this. (just these are inputs) I registered *flair
and t1 to DIR *for every patient.
(My manual lesion masks are on DIR imaging.) I controlled the registrations

At the beginning i didnt change initial threshold of run_samseg. (default
value)

I created a binary lesion mask using different threshold.

*threshold *0.1= *dice* 0,604
*threshold *0.05= *dice *0.611
*threshold *0.001 = *dice *0.599

Do you have any recommendations to increase the dice? It seems that with
this way It can't go up about 0.6

Best,
Dilek
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