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Aloha,

Mahalo for your response! What do you use for normalization between subjects?

Mālama Pono,

Krystalyn Edwards-Calma

> On Jun 27, 2025, at 5:23 AM, Douglas N. Greve <dgr...@mgh.harvard.edu> wrote:
> 
> This is not necessarily a problem. The "e" in eTIV means "estimate". It is a 
> slight hack where the registration to MNI space is used to compute an 
> estimate of the TIV, so it is not based on a segmentation or any real image 
> processing, so it is sometimes quite off. This ratio was really just meant to 
> be a flag to catch your attention. Now that it has it, just look at the skull 
> stripping and see if it looks ok. If it does, then ignore the flag.
> 
>> On 6/25/2025 6:49 PM, Krystalyn Edwards-Calma wrote:
>>         External Email - Use Caution
>> 
>> Aloha,
>> 
>> I am using Version 7.4.1. After running recon-all for multiple subjects, I 
>> noticed the Brain mask is larger than the intracranial volume (Mask-to-eTIV 
>> > 1). I attempted multiple different skull stripping methods, however, the 
>> mask-to-eTIV is always > 1. Any suggestions on how to fix this? Mahalo for 
>> your help.
>> 
>> Malama pono,
>> 
>> Krystalyn Edwards-Calma
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