-----BEGIN PGP SIGNED MESSAGE----- Hash: SHA1 Phil Henshaw on 12/07/2007 01:42 PM: > PH: I was impressed with the clarity of the abstract and their not > confusing biology, lab chemistry and computer model references. Figure > 1 puzzles me though. I get your suggestion that this shows a way people > are using new visualization techniques to compare models. I don't > understand how highly complex comparisons of test tube and computer > based things would make them look so very much alike unless both are > parametric data displays of a sort not described, though. Comparing > hugely complicated systems does need visualization help, certainly, but > if that's what makes the images look so much alike it should be > mentioned. Still, what I get from the picture is that they give > themselves an A+. I don't see how their model recreates some features > of the natural process and interestingly leaves others out. It's > importantly that art of making what you've failed to account for > interesting, rather than hiding it, that I find missing in lots of > studies.
Just for clarity, it's a cartoon and not a visualization. The diagram is merely intended to give a visual impression of the iterative process being used. The gray smudges and spots representing targeted attributes do not map to particular behaviors of the in vitro or in silico models. So, it's not that they're giving themselves an A+, they're just trying to say that the first model (the gray circle in A) is falsified because it doesn't exhibit the behavior indicated by the spot labeled "a" even though it exhibits the behaviors labeled "t". The second model (not just the same model with different parameter values), pointed to by "2" in B is _also_ falsified because it does not exhibit "a". However, there are indications that model 2 is "better" than model 1 because it exhibits those two behaviors indicated by the spots that are closer in the behavior space to "a". The subsequent model 3 is _validated_ because it exhibits behaviors "t" and "a". > So, here's to all 'bad' models...! may we survive them...:-) Perfect! I'll make that toast over my next pint. - -- glen e. p. ropella, 971-219-3846, http://tempusdictum.com The only good is knowledge and the only evil is ignorance. -- Socrates -----BEGIN PGP SIGNATURE----- Version: GnuPG v1.4.6 (GNU/Linux) Comment: Using GnuPG with Mozilla - http://enigmail.mozdev.org iD8DBQFHWcv/ZeB+vOTnLkoRAsDcAJ97VJWKqW1O7XZjfvRqJccektNC3QCgn1fV TJh+giOWVLF9kvPtmpfVoi0= =sxCj -----END PGP SIGNATURE----- ============================================================ FRIAM Applied Complexity Group listserv Meets Fridays 9a-11:30 at cafe at St. John's College lectures, archives, unsubscribe, maps at http://www.friam.org
