Glen,

 

Yes.  And that is why reverse transcription was such a big deal -- Because it 
violates Weismann's Doctrine 
<https://link.springer.com/article/10.1007/s00114-014-1164-4> .  I think most 
contemporary biologists still think that those violations are the province of 
the very small, but with all we know about epigenetics these days, the whole 
argument is starting to feel cranky and old-fashioned.  

 

When I try to think about “downward-causation” my imagination always fails.  
Think of four sticks, arranged in a square.  They are very flimsy.  Now add a 
fifth stick, a diagonal.  The whole becomes much more sturdy, right  Now, this 
is a clear instance of an emergent property, no?  And the freedom of motion of 
the other four sticks has been constrained by the configuration of the whole, 
right?  But where is “downward-causation”, here?  Or choose your own example.  
How exactly does “downward causation” work?  It puts my mental knickers in a 
twist.  

 

Nick.  

 

Nicholas Thompson.

Emeritus Professor of Ethology and Psychology

Clark University

[email protected]

https://wordpress.clarku.edu/nthompson/

 

 

-----Original Message-----
From: Friam <[email protected]> On Behalf Of u?l? ???
Sent: Monday, July 20, 2020 9:32 AM
To: FriAM <[email protected]>
Subject: Re: [FRIAM] better simulating actual FriAM

 

I don't know quite how to parse this. By "original gen-phen distinction", do 
you simply mean DNA->RNA? What do you mean by "original"? And would reverse 
transcription imply information flow from phen to gen?

 

FWIW, when I talk about downward causation, I'm not assuming irreducible 
phenomena (strong emergentism). Mostly, I think of landscape change. Just to 
prove I am reading it [⍢], I'll cite EricS' (and Morowitz') hierarchy of matter 
phases, wherein as the temperature goes down, prior freezes set the context for 
what *could* be the case for future freezes. That's a macro thing constraining 
the micro thing. It doesn't seem so much to me like "information traveling" as 
limited freedom ... a weak kind of forcing structure. But if we talk in terms 
of variability/uncertainty/wiggle, then it sounds a bit like a *loss* of 
information. Downward causation from macro to micro might map well to a 
reduction in the information content of the micro. There would have to be some 
transient, though. Before the macro constraints were strong enough, the 
information content was high. After they are strong enough, the micro content 
is lower. Is a reduction in information, itself, information? 2nd order 
information?

 

 

[⍢] [In]Comprehension notwithstanding.

 

On 7/17/20 5:35 PM,  <mailto:[email protected]> [email protected] 
wrote:

> Notice, FWIW, that the original gen-phen distinction was understood to forbid 
>  any information traveling from phen to gen.

 

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