Hello, Despite the warning message, it is OK to lift from human to mouse. However, the more diverged the two species are, the less reliable liftOver is.
Alternatively, you can go to the human genome browser (assembly Mar. 2006, hg18) and look at the Mouse Net track. This track shows orthologous regions between human and mouse. Please don't hesitate to contact the mail list of you require further assistance. Katrina Learned UCSC Genome Bioinformatics Group jchl tu wrote: > HI everyone: > for I want to lift many regions of human to mouse using LiftOver, I > download LiftOver executable file from > "http://hgdownload.cse.ucsc.edu/admin/exe/linux.i386/";. > execute it to present a help file. which worry me most is the warning > message in help file as below: > WARNING: liftOver was only designed to work between different > assemblies of the same organism, it may not do what you want > if you are lifting between different organisms. > > My question is Can I use liftover to find conservations region between > human and mouse? > _______________________________________________ > Genome maillist - [email protected] > https://lists.soe.ucsc.edu/mailman/listinfo/genome > _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
