Hi Kraig,

There are instructions for setting up your shell environment and 
building the source, along with a few common problems and their 
solutions, in the source tree in the file:
kent/src/product/README.building.source

This is also online, here:
http://genome-source.cse.ucsc.edu/gitweb/?p=kent.git;a=blob;f=src/product/README.building.source

If you have further questions, please feel free to send them back to 
this list ([email protected]).

--
Brooke Rhead
UCSC Genome Bioinformatics Group



On 11/17/10 08:04, Kraig Stevenson wrote:
> I'm having some difficulty building the source utilities on my Mac. The
> online resource at UCSC is for building and installing on Linux/Unix
> systems. Specifically, I am using version 10.6.5. I know this is Unix-based,
> but is there a way to build the source on a Mac?
> 
> Thanks!
> 
> -Kraig
> 
> On Tue, Nov 16, 2010 at 7:54 PM, Mary Goldman <[email protected]> wrote:
> 
>> Hi Kraig,
>>
>> You can get chainSwap utility as a part of our source downloads.
>> You can find instructions about downloading and installing kent source
>> utilities here:
>>
>> http://hgdownload.cse.ucsc.edu/downloads.html#source_downloads
>> http://genome.ucsc.edu/admin/jk-install.html
>>
>> With the actual source download residing here:
>> http://hgdownload.cse.ucsc.edu/admin/jksrc.zip
>>
>> I hope this information is helpful.  Please feel free to contact the mail
>> list again if you require further assistance.
>>
>> Best,
>> Mary
>> ------------------
>> Mary Goldman
>> UCSC Bioinformatics Group
>>
>>
>>
>> On 11/16/10 2:29 PM, Kraig Stevenson wrote:
>>
>>> To whom it may concern:
>>>
>>> My name is Kraig Stevenson, and I am a PhD student in bioinformatics at
>>> the
>>> University of Michigan. I would like to request the chainSwap utility.
>>>
>>> Thank you very much!
>>>
>>> -Kraig
>>>
>>> ---------- Forwarded message ----------
>>> From: Jim Kent<[email protected]>
>>> Date: Tue, Nov 16, 2010 at 3:30 PM
>>> Subject: Re: Reverse chain files for LiftOver tool
>>> To: Kraig Stevenson<[email protected]>
>>>
>>>
>>> In general you will want to generate a separate chain file for the
>>> reverse.
>>>  I _think_ you'll end up with just a 5% less good result if you basically
>>> swap the target and query sequences in the chain.  We have a chainSwap
>>> utility at UCSC that will do that.  If this is the route you decide to
>>> take,
>>> please contact [email protected] to get the utility.  It'd be best if
>>> you
>>> got in contact with whoever generated the chain file in the first place
>>> though.
>>>
>>> Take care,
>>> Jim
>>>
>>> On Nov 16, 2010, at 11:28 AM, Kraig Stevenson wrote:
>>>
>>> Hello Dr. Kent,
>>>
>>> My name is Kraig Stevenson, and I am a bioinformatics PhD student at the
>>> University of Michigan. I have extensively used your LiftOver tool to go
>>> between species, and I currently have a chain file that lifts coordinates
>>> from one (non-sequenced) species to a (sequenced) species (this was given
>>> to
>>> us by a collaborator). Now I would actually like to go in the opposite
>>> direction, but I am not sure how to go about this. Is there a way to
>>> reverse
>>> the chain file so that the LiftOver tool could accomplish this task? Could
>>> the LiftUp tool be used in this situation?
>>>
>>> Any advice you might have would be greatly appreciated.
>>>
>>> Best regards,
>>>
>>> -Kraig
>>>
>>>
>>>
>>
>>
> 
> 
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