Hi Everyone I am making my question more clear.
I have a question which might be a simple one for you guys So since i am working on ribosomal protein genes(around 80 in humans), i have managed to extract the snps at various locations in all those 80 genes. This snps are basically genomic in origin and they are coding. I will just show you guys the table. #bin chrom chromStart chromEnd name transcript frame alleleCount funcCodes alleles codons peptides mol_type class function 887 chr22 39708987 39708988 rs2014840 NM_000967 2 2 8,42, G,T, GGA,GTA, G,V, genomic single missense Now as you can see their is a change of peptide from G(glycine) -> V(valine) for snp rs2014840. What i am interested in is the fact that i need to find where this change is actually occurring in the peptide seq. In other words i want to know which Glycine(G) residue gets changed to Valine(V). I am making my question more clear. Now suppose i have a seq of Amino Acids MACARPLISVYSEK*G*ESS*G*KNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQ PYAVSELA*G*HQTSAESW*G*T*G*RAVARIPRVR*GGG*THRS*G*Q*G*AF*G*NMCR *GG*RMFA Now what i want to know is which G(glycine) in the above seq is changing into V(valine) I have a huge list of my genes and each genes have snps like these. It would be very nice of you to help me out in this.. Regards VARUN _______________________________________________ Genome maillist - [email protected] https://lists.soe.ucsc.edu/mailman/listinfo/genome
