Dear Michael Harms,

Thanks for your reply. I will consider your suggestion seriously and will
think over to see if my study can take an alternate route. Thanks!

Regards,
Ranga

On Fri, Oct 10, 2014 at 12:13 PM, Harms, Michael <[email protected]> wrote:

>
>  Hi,
> There are all sorts of reasons that you could get spatially specific
> results between different scanners/protocol, including differing spatial
> profiles of the SNR, differing gradient nonlinearities, etc.  So, I don't
> see how looking for spatial specificity is going to solve of the problem of
> trying to compare data collected on two different scanners.
>
>  cheers,
> -MH
>
>   --
> Michael Harms, Ph.D.
>  -----------------------------------------------------------
> Conte Center for the Neuroscience of Mental Disorders
> Washington University School of Medicine
> Department of Psychiatry, Box 8134
> 660 South Euclid Ave. Tel: 314-747-6173
> St. Louis, MO  63110 Email: [email protected]
>
>   From: Ranga Deshpande <[email protected]>
> Date: Friday, October 10, 2014 12:07 PM
> To: "Harms, Michael" <[email protected]>
> Cc: Greg Burgess <[email protected]>, "[email protected]" <
> [email protected]>
>
> Subject: Re: [HCP-Users] Reg. DPARSF
>
>   Dear Michael Harms,
>
>  Thanks for your reply. I know that such a question is going to arise
> once I do the processing and get the results, but scanner/protocol effects
> must be spatially widespread and not specific. If strong specific effects
> are observed then that will make an interesting result!
>
>  Regards,
> Ranga
>
> On Fri, Oct 10, 2014 at 8:09 AM, Harms, Michael <[email protected]> wrote:
>
>>
>>  Hi Ranga,
>> Separate from the issue of HCP vs. DPARSF processing pipelines, you are
>> going to have a very difficult time comparing HCP data to separate disease
>> population data that was collected on a different scanner and with a
>> different acquisition protocol.  For any differences that you might find,
>> how will you be able to know that it isn't a scanner/protocol effect?
>>
>>  cheers,
>> -MH
>>
>>   --
>> Michael Harms, Ph.D.
>>  -----------------------------------------------------------
>> Conte Center for the Neuroscience of Mental Disorders
>>  Washington University School of Medicine
>>  Department of Psychiatry, Box 8134
>> 660 South Euclid Ave. Tel: 314-747-6173
>> St. Louis, MO  63110 Email: [email protected]
>>
>>   From: Ranga Deshpande <[email protected]>
>> Date: Friday, October 10, 2014 12:36 AM
>> To: Matt Glasser <[email protected]>, Greg Burgess <
>> [email protected]>
>> Cc: "[email protected]" <[email protected]>
>> Subject: Re: [HCP-Users] Reg. DPARSF
>>
>>   Dear Matthew Glasser and Greg Burgess,
>>
>>  Many thanks for your replies. It really helped.
>>
>>  I am trying to use the HCP data as controls, while I have another
>> separate disease population data. I need to perform statistical analysis
>> between the HCP controls and my disease population. My data has undergone
>> the DPARSF pipeline, so I felt that it would be better if I pre-processed
>> even the HCP data through the same pipeline.
>>
>>  But now I find that there are a multitude of issues in doing that. So I
>> have proceeded with using the ICA-FIX data itself.
>>
>>  Thanks again for your responses!
>>
>>  Best Regards,
>> Ranga
>>
>> On Thu, Oct 9, 2014 at 11:32 AM, Greg Burgess <[email protected]>
>> wrote:
>>
>>> Hello Ranga,
>>>
>>> There are definitely aspects of the pre-processing that we have done
>>> within HCP, because the specifics are quite tricky to get right. If you
>>> want more on those specifics, you can review the Glasser et al. (2013)
>>> Neuroimage paper and/or the code and scripts that were recently released (
>>> http://humanconnectome.org/about/pressroom/project-news/hcp-processing-pipelines-released/
>>> ).
>>>
>>> If you want to do additional preprocessing on your data (e.g., different
>>> temporal filtering or spatial smoothing), you will need to do that on the
>>> NIFTI or CIFTI preproc files. I’m not familiar with DPARSF, but it appears
>>> to want DICOM files as inputs. You might want to migrate to using FSL and
>>> workbench for better compatibility with the HCP data.
>>>
>>> --Greg
>>>
>>> ____________________________________________________________________
>>> Greg Burgess, Ph.D.
>>> Staff Scientist, Human Connectome Project
>>> Washington University School of Medicine
>>> Department of Anatomy and Neurobiology
>>> Phone: 314-362-7864
>>> Email: [email protected]
>>>
>>> On Oct 8, 2014, at 6:53 PM, Glasser, Matthew <[email protected]>
>>> wrote:
>>>
>>> > I wouldn’t recommend trying to redo the preprocessing, as getting that
>>> right is complicated.  Why not use the FIX cleaned data and focus on
>>> whatever analysis you are interested in doing?
>>> >
>>> > Peace,
>>> >
>>> > Matt.
>>> >
>>> > From: Ranga Deshpande <[email protected]>
>>> > Date: Wednesday, October 8, 2014 at 6:48 PM
>>> > To: "[email protected]" <[email protected]>
>>> > Subject: [HCP-Users] Reg. DPARSF
>>> >
>>> > Hi,
>>> >
>>> > I am a graduate student at Auburn University MRI Research Center,
>>> Auburn, AL.
>>> > I am currently planning to use some of the HCP 500 data. I am
>>> attempting to use Data Processing Assistant for Resting State fMRI (DPARSF)
>>> (see: http://www.ncbi.nlm.nih.gov/pubmed/20577591 and
>>> http://rfmri.org/DPARSF) to perform pre-processing.
>>> >
>>> > However, I am encountering one error after the other, ranging from
>>> non-detection of data, mal-detection of data (zero-timepoints error), "data
>>> has orientation problems so cannot realign" errors and other non-traceable
>>> errors. I have tried using unprocessed data (pre-processing from scratch),
>>> pre-processed data and even ICA-fix data. In all cases I have issues using
>>> DPARSF.
>>> >
>>> > Has anyone had the same issue of using DPARSF to analyze HCP500 data?
>>> >
>>> > Regards,
>>> > Ranga
>>> > _______________________________________________
>>> > HCP-Users mailing list
>>> > [email protected]
>>> > http://lists.humanconnectome.org/mailman/listinfo/hcp-users
>>> >
>>> >
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