HCP processing does not conduct low-pass filtering for either minimally 
preprocessed or FIX-cleaned data. However, low pass temporal filtering is 
probably not necessary, and is not recommended by the HCP consortium.

One goal of FIX is to selectively remove high frequency noise, but keep other 
high frequency sources that are more likely to be signal. The FIX-ICA denoising 
identifies and removes components containing high frequencies, but also 
requiring signatures of noise. Most in the HCP consortium argue that this is 
preferable to filtering potential signal, and preferable to using low pass 
temporal filters that can smooth the data and run the risk of artifactually 
inflating connectivity estimates.

--Greg

____________________________________________________________________
Greg Burgess, Ph.D.
Staff Scientist, Human Connectome Project
Washington University School of Medicine
Department of Psychiatry
Phone: 314-362-7864
Email: [email protected]

> On Nov 4, 2016, at 1:48 PM, nailin yao <[email protected]> wrote:
>
> Hi ,
>
> I'm trying to do analysis on the resting fMRI output from HCP-Pipeline and 
> ICAFIX. May I know if these preprocessing include low-pass filtering (with 
> .01~0.1Hz signal left for resting analyzing)? Or I need to do it separately? 
> Thank you very much!
>
> Best,
> Nailin
>
> --
> Nailin Yao,  PhD
>
> Postdoctoral Associate
> Department of Psychiatry, Yale University
>
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> HCP-Users mailing list
> [email protected]
> http://lists.humanconnectome.org/mailman/listinfo/hcp-users
>


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