>
> I meant the grass sickness Laree, what did it say?  Is it something we
> have here?
> Janice

Yes, that's what I was talking about. Hopefully this will come through
- I copied it into the email - It's from "Equine World UK" web site

Articles: Grass Sickness

 Grass sickness is a disease that affects all type of horses, ponies
and donkeys. The disease was first recognised in 1907 in Dundee,
Scotland and now occurs in all parts of Great Britain. The disease is
found in Europe and has recently been reported in Ireland and North
America. A very similar disease also occurs in Chile, Argentina (where
it is called mal seco or dry sickness) and the Falklands. In the UK,
the disease is more prevalent in eastern counties and the incidence
rate in certain regions is as high as 1 in 200 horses.

The disease can affect any equine breed that has access to grass.
Statistical studies show no prevalence for breed or sex although
younger horses (2-7 year olds) are more susceptible. The disease has
not been reported in suckling foals and it may be that older horses
have built up immunity to the causative agent. Grass sickness is
associated with cool dry weather and more cases are seen between
April-July with a peak in May.

A significant number of cases have a recent history of stress. These
include recent change of owner and subsequent move of pasture,
introduction into a new herd or other factors such as breaking and
castration.

Despite a large amount of research over the last century the cause of
the disease has not been identified. The type of damage caused to the
nervous system indicates that some sort of toxin is involved and
poisonous plants, chemicals, different bacterial species and viruses
are amongst the possible causes that have been investigated. Grass
sickness is not contagious and the cause of the disease is likely to
be multifactorial i.e. caused by a combination of conditions and/or
agents. Current research includes investigation of the association of
the bacterium Clostridium botulinum with the disease and into the
cyanide-producing properties of white clover.

There are three main forms of grass sickness: acute, subacute and
chronic. The acute and subacute forms are invariably fatal but
encouraging progress has been made in managing selected chronic cases
of the disease. Symptoms of the acute phase can include muscle
tremors, salivation and dysphagia (difficulty in swallowing).
Euthanasia/death occurs within 48 hours. In the subacute form,
symptoms are less severe than the acute although the majority will die
or require euthanasia within 7 days. As the disease progresses
symptoms can also include colic, reduced gut motility, colonic
impaction and weight loss. A typical sign of a chronic case is severe
weight loss with the horse appearing very 'tucked up'.

It can be very difficult for a veterinary surgeon to distinguish the
early stages of grass sickness from other conditions that cause
similar symptoms. There is no definitive diagnostic test in the live
horse, although urine analysis and one involving phenylephrine eye
drops (both developed at Edinburgh University) may prove useful.
Definitive diagnosis is only obtained postmortem by examination of the
nerve ganglia.

The Equine Grass Sickness Fund (EGSF), which was established in 1988,
is a registered charity that helps to fund and co-ordinate scientific
research into the cause, treatment and diagnosis of this distressing
disease.

The EGSF has funded many projects in addition to two PhD students
based at Edinburgh University. Articles about current and past
research as well as information, advice and merchandise can be found
on the charity's informative website.

Until recently the mortality rate for chronic cases was approaching
100%. The experience gained at Edinburgh University Veterinary School
has increased the survival rate for selected chronic cases to
approximately 70% and their care regimes have been successfully used
by clinicians elsewhere. The mainstay of the treatment is good nursing
care i.e. constant human contact and the feeding of palatable, easily
chewed, high-energy food. The veterinary school has a dedicated grass
sickness nurse, funded by the ILPH, and the long-term care of chronic
cases is subsidised by funding provided by the Equine Grass Sickness
Fund.

As mentioned earlier, the possible association between Clostridium
botulinum type C/D and grass sickness is currently under investigation
at Edinburgh University. The organism and its toxins are extremely
difficult to detect and studies have been focused in two ways:
detection of toxin and of the bacterium and detection of specific
antibodies. Results are highly indicative of the involvement of this
organism in the cause of the disease. This is encouraging as it raises
the possibility of development of a vaccine in the future.

However, much more research is required and is expensive! If you would
like to find out more, become involved or need cards and gifts please
visit the EGSF website where you can purchase items to help support
the charity. This disease affects all type of horses and ponies and
therefore all types of horse owners. The Equine Grass Sickness Funds
need YOUR help in raising money to find the cause of this devastating
disease.


-- 
Laree in NC
Doppa & Mura
Simon, Sadie and Sam (the "S" gang)

"Yet when all the books have been read and reread, it boils down to
the horse, his human companion, and what goes on between them." -
William Farley

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