>Are there any better ideas of hardware requirements beyond large and small?

To keep out of trouble on the mailbox server, spend money on two or more 
caching LVD SCSI controllers and 160 mb/sec disks vs spending the money on 
32-way 50 GHz Xeons.

RAID1 for speed.  (RAID5 is slower when writing, but ok when doing database 
work where 90% of disk i/o is read.)  Disk i/o for mailboxes and mailqueue 
and logging is close to 50:50 read:write.

separate disks and/or partitions for system, system swap, mailqueue+logging 
(or send the logging off the box to a syslog server) and mailboxes.  plus 
have tons of, double?, spare disk space versus calculated storage so the 
necessary defragging runs as fast as possible.

>Starting with larger and moving to smaller... what's the range that we're
>talking about here for 100k-120k users?

If admins here who run these big systems won't say what they run as 
hardware, I'm certainly can't say.

>Assuming inbound, outbound and
>client SMTP is being handled by a different box(es).
>
>Quad PIII 700Ghz / 2GB RAM

if you have the $, do it.  But have enough $ for the caching, 64-bit SCSI 
controllers (128 mb per controller) and RAID1 disks.

>Dual PIII 1Ghz / 1GB RAM
>Dual PIII 700Mhz / 1GB RAM
>PIII 1Ghz / 1GB RAM
>PII 500 Mhz / 1GB RAM

I would start with 2 gb no matter what the CPU was.  The disks subsystem is 
more important than the CPU.

>Also, regarding anti-virus for web-mail users... I've been told not to use
>declude on the same box.

Well, not a box with 100K users and 500k msgs/day, but for small/medium 
servers, it obviously leaves enough machine for Imail to work just fine.

IMGate with AV is only $560/year, unlimited users/domains, and is proven in 
high-volumes like yours. I can give you references.  I can build the 
machine, too.

>Are there any other alternatives that would
>protect email being shared among users on that same box?

As Scott said, infection via webmail attachements is quite rare, not the 
usual vector.  You have many issues to address before you get to that one. 
It's not a show-stopper.

Len



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