http://www.smh.com.au/technology/sci-tech/i-can-create-neanderthal-baby-20130122-2d3u7.html

'I can create Neanderthal baby'
  Date  January 22, 2013 - 9:20AM 
Rebecca Smith in London
Neanderthals could create their own culture and political force in the world, 
says Harvard scientist George Church



 
Neanderthal Man Photo: Supplied

A Harvard scientist has said it would be possible to clone a Neanderthal baby 
from ancient DNA if he could find a woman willing to act as a surrogate.

The process would not be legal in many countries and would involve using DNA 
extracted from fossils.

George Church, a genetics professor of Harvard School of Medicine, said that 
the process was possible and that far from being brutal and primitive, 
Neanderthals were intelligent beings.

They are believed to be one of the relatives of modern man and became extinct 
33,000 years ago. He added that altering the human genome could also provide 
the answers to curing diseases such as cancer and HIV, and hold the key to 
living to 120.

He told Der Spiegel, the German magazine: "I have already managed to attract 
enough DNA from fossil bones to reconstruct the DNA of the human species 
largely extinct. Now I need an adventurous female human."

The professor claims that he could introduce parts of the Neanderthal genome to 
human stem cells and clone them to create a foetus that could then be implanted 
in a woman.

Professor Church helped start the Human Genome Project that mapped human DNA 
and is well respected in the field. His comments will surprise most geneticists 
who believe that cloning humans is unacceptable. It is illegal in Britain.

Professor Church said: "We can clone all kinds of mammals, so it's very likely 
that we could clone a human. Why shouldn't we be able to do so?"

He added: "Neanderthals might think differently than we do. We know that they 
had a larger cranial size. They could even be more intelligent than us.

"When the time comes to deal with an epidemic or getting off the planet or 
whatever, it's conceivable that their way of thinking could be beneficial. They 
could maybe even create a new neo-Neanderthal culture and become a political 
force. The main goal is to increase diversity. The one thing that is bad for 
society is low diversity."

Professor Church said the technique would involve artificially creating DNA 
from fossilised material and introducing this into human stem cell lines.

He discusses his idea in his latest book, Regenesis: How Synthetic Biology Will 
Reinvent Nature and Ourselves.

He rules out recreating older human ancestors or dinosaurs, as was the subject 
of the Jurassic Park films, because the age limit of useful DNA is about one 
million years, he said.

He told the magazine: "One of the things to do is to engineer our cells so that 
they have a lower probability of cancer.

"And then once we have a lower probability of cancer, you can crank up their 
self-renewal properties, so that they have a lower probability of senescence 
[ageing]."

The Daily Telegraph


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