Hi Mahmoud
Have you checked using other tools on your OTRS system (eg something like 
‘ldapsearch’) that you do have access to the AD LDAP server still?
‘Connection refused’ does sound as if the basic network socket isn’t being 
established, so could it be that someone has changed a firewall setting between 
your OTRS system and the AD LDAP server,  or decided to enforce SSL access? 
Other basic tools like ping or traceroute could be useful too just in case 
something is preventing access to your DC now.

You might try using SSL – I have found that to get this to work I need to 
specify the host using a URL format rather than just a hostname – eg in line 98 
of your Config.pm file you could change

Host => 'dc.hotciscolabs.com',

to

Host => 'ldaps://dc.hotciscolabs.com',

and in line 121 change

port    => 389

to

port    => 636

That should make OTRS use SSL for the lookup (in version 3.3 anyway).
Regards
Phil

From: Mahmoud Ramadan Ali [mailto:[email protected]]
Sent: 12 November 2014 15:46
To: OTRS::ITSM User questions and discussions
Subject: Re: [itsm] OTRS and LDAP Integration get broken

any updates dears ! i'm stuck now

On Tue, Nov 11, 2014 at 9:37 PM, Mahmoud Ramadan Ali 
<[email protected]<mailto:[email protected]>> wrote:
Hii Dears,
Thanks for the reply but i checked the user and it is not locked or disabled 
also i'm using Microsoft active directory and do not have ssl configured ...i 
added the user to the administators and domain admins group without success...i 
have attached my Config.pm file so u can check it. Please this is urgent so any 
assistance will be appreciated.

On Tue, Nov 11, 2014 at 11:25 AM, Patrick Bloem 
<[email protected]<mailto:[email protected]>> wrote:
Hi Mahmoud,

do you check the Active Directory User for the connection?
Maybe is the user is disable or banned from the inactivity policy.

With best regards
Patrick Bloem
System Administrator

Von: [email protected]<mailto:[email protected]> 
[mailto:[email protected]<mailto:[email protected]>] Im Auftrag von 
Mahmoud Ramadan Ali
Gesendet: Dienstag, 11. November 2014 10:18
An: OTRS::ITSM User questions and discussions
Betreff: Re: [itsm] OTRS and LDAP Integration get broken

Hiii Marcel,
Thanks for the reply but no i'm not using SSL...i'm integrating this with MS 
Active directory and the integration worked fine for sometime then get 
broken...i have uploaded my config file so you can check it ..and thanks in 
advance...

On Tue, Nov 11, 2014 at 6:56 AM, Marcel Schulte 
<[email protected]<mailto:[email protected]>> wrote:
Hi Mahmoud,

do you connect to LDAP or LDAPS (with SSL)? In case of LDAPS it could have 
happened the SSL certificate of your LDAP server has changed and your OTRS does 
not know how to verify this new cert...

HTH,
Marcel

Mahmoud Ramadan Ali 
<[email protected]<mailto:[email protected]>> schrieb 
am Mon Nov 10 2014 at 20:09:21:
Hi everyone
I've integrated OTRS and LDAP and it worked for a sometime but the integration 
get broken and i'm reciving this error message...any help please how to solve 
this ?!
Nov 10 20:00:38 localhost OTRS-CGI-62[3438]: 
[Error][Kernel::System::Auth::LDAP::Auth][Line:167]: Can't connect to 
dc.hotciscolabs.com<http://dc.hotciscolabs.com>:\
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