Oh, that is far in the opposite direction now -- too much debug information :) You do not need to turn on debug messages; normal messages are enough.
The problem comes from: Rscript --verbose --no-save --no-restore "/Applications/LyX 2.app/Contents/Resources/scripts/lyxsweave.R" becomes '/Library/Frameworks/R.framework/Versions/2.13/Resources/bin/R --slave --no-restore --no-save --no-restore --file=/Applications/LyX 2.app/Contents/Resources/scripts/lyxsweave.R I do not know why R removed the quotes around the --file argument, but FWIW, can you upgrade R to the latest version before you proceed? Also update LyX if you can. Both LyX and R are old in your system. The other thing is to make sure you did not hack at the Sweave module by yourself; check the preferences file in your LyX User directory (should not contain anything about Sweave there). I do not use Mac OS, so it is difficult for me to reproduce the problem. Regards, Yihui -- Yihui Xie <xieyi...@gmail.com> Phone: 515-294-2465 Web: http://yihui.name Department of Statistics, Iowa State University 2215 Snedecor Hall, Ames, IA On Thu, Jul 26, 2012 at 10:40 AM, Hobbs,Tom <tom.ho...@colostate.edu> wrote: > Sorry--I thought the message I sent was the one you needed. I set all of > the debug messages to Yes and it appears that this is the one causing > problems: > > 08:34:14.849: Fatal error: cannot open file '/Applications/LyX': No such > file or directory > > There is a file in my /Applications directory for LyX 2.app > > I included the full message list below. > > I have done the Reconfigure and the problem remains. > > Thanks very much for your help. > > Tom